LSBio
Polyclonal Rabbit anti-Mouse ATF4 Antibody (N-Terminus, IHC, WB)

Anti-ATF4 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Polyclonal Rabbit anti-Mouse ATF4 Antibody (N-Terminus, IHC, WB)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot
Reactivity:Human, Mouse
Format:Liquid
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$470.00each
Catalog Number: LS-B3517-50

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Overview

Description
ATF4 antibody LS-B3517 is an unconjugated rabbit polyclonal antibody to ATF4 (N-Terminus) from mouse. It is reactive with human and mouse. Validated for IHC and WB. Cited in 2 publications.
Application
IHC, IHC-P, WB
Reactivity
Hu, Ms
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
ATF4 | CREB-2 | CREB2 | TXREB | DNA-binding protein TAXREB67 | TAXREB67
Recommended Dilution: IHC-P
5 µg/ml
UniProt Number
P18848
SwissProt
P18848

Target

Target
ATF4
Antigen Species
Mouse
Specificity
Mouse ATF4
Epitope
Mouse ATF4
Gene Name
ATF4

Antibody

Host Species
Rabbit
Clonality
Polyclonal
Origin Species
Human

Immunogen

Immunogen
Synthetic peptide from N-Terminus of mouse ATF4 (Q61328, NP_033846). Percent identity by BLAST analysis: Mouse (100%).
Immunogen Type
Synthetic Peptide (Linear)

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, 0.09% sodium azide, 2% sucrose
Concentration
0.5 mg/mL
Volume
50 Microliter
Animal Free
No
Carrier-Free
Yes
Preservative
Yes
Purification Method
Affinity Purified

Storage & Handling

Storage Conditions
Short term: Store at 2-8°C. Long term: Aliquot and store at -20°C. Avoid freeze/thaw cycles.
Recommended Storage Buffer
PBS

A thrombospondin-dependent pathway for a protective ER stress response. Lynch JM, Maillet M, Vanhoutte D, Schloemer A, Sargent MA, Blair NS, Lynch KA, Okada T, Aronow BJ, Osinska H, Prywes R, Lorenz JN, Mori K, Lawler J, Robbins J, Molkentin JD. Cell. 2012 Jun;149:1257-68.

PubMed: 22682248 · PMC: PMC3372931


The Transcription Factor ATF4 Promotes Expression of Cell Stress Genes and Cardiomyocyte Death in a Cellular Model of Atrial Fibrillation. Freundt JK, Frommeyer G, Wötzel F, Huge A, Hoffmeier A, Martens S, Eckardt L, Lange PS. BioMed research international. 2018 May;2018:3694362.

PubMed: 30003094 · PMC: PMC5996409

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