LSBio
Polyclonal Rabbit anti-Human USP6 / HRP1 Antibody (IHC, IF, WB)

Positive WB detected in:Rat kidney tissue;All lanes:USP6 antibody at 4?g/ml;Secondary;Goat polyclonal to rabbit IgG at 1/50000 dilution;Predicted band size: 159,122,90 KDa;Observed band size: 159 KDa;

Polyclonal Rabbit anti-Human USP6 / HRP1 Antibody (IHC, IF, WB)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Enzyme-Linked Immunosorbent Assay, Immunofluorescence, Immunohistochemistry (general), Western Blot
Reactivity:Human, Rat
Format:Liquid
See all Human USP6 / HRP1 antibodies →
$300.00each
Catalog Number: LS-C500002-50

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Overview

Description
HRP1 antibody LS-C500002 is an unconjugated rabbit polyclonal antibody to HRP1 (USP6) from human. It is reactive with human and rat. Validated for ELISA, IF, IHC and WB.
Application
ELISA, IF, IHC, WB
Reactivity
Hu, Rt
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee. ✓
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
Proto-oncogene TRE-2 | Tre-2 | Tre-2 oncogene | Ubiquitin specific protease 6 | Ubiquitin thioesterase 6 | USP6 | Deubiquitinating enzyme 6 | HRP1 | Hyperpolymorphic gene 1 | TBC1D3 and USP32 fusion | TRE2 | Ubiquitin thiolesterase 6 | USP6-short
UniProt Number
P35125
NCBI GenBank
NM_004505 | NP_004496.2
SwissProt
P35125

Target

Target
Human USP6 / HRP1
Antigen Species
Human
Epitope
Deubiquitinase with an ATP-independent isopeptidase activity, cleaving at the C-terminus of the ubiquitin moiety. Catalyzes its own deubiquitination. In vitro, isoform 2, but not isoform 3, shows deubiquitinating activity. Promotes plasma membrane localization of ARF6 and selectively regulates ARF6-dependent endocytic protein trafficking. Is able to initiate tumorigenesis by inducing the production of matrix metalloproteinases following NF-kappa-B activation.
Gene Name
USP6

Antibody

Host Species
Rabbit
Clonality
Polyclonal
Isotype
IgG

Immunogen

Immunogen
Recombinant Human Ubiquitin C-Terminus hydrolase 6 protein (1122-1359AA)
Immunogen Type
Recombinant Immunogen

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Preservative
Yes
Purification Method
Protein G Affinity

Storage & Handling

Storage Conditions
Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.
Recommended Storage Buffer
PBS

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