LSBio
Polyclonal Rabbit anti-Human TRADD Antibody (IHC, IF, WB)

Positive WB detected in:K562 whole cell lysate,Rat kidney tissue;All lanes:TRADD antibody at 4?g/ml;Secondary;Goat polyclonal to rabbit IgG at 1/50000 dilution;Predicted band size: 35,28 KDa;Observed band size: 35 KDa;

Polyclonal Rabbit anti-Human TRADD Antibody (IHC, IF, WB)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Enzyme-Linked Immunosorbent Assay, Immunofluorescence, Immunohistochemistry (general), Western Blot
Reactivity:Human, Rat
Format:Liquid
See all Human TRADD antibodies →
$300.00each
Catalog Number: LS-C500884-50

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Overview

Description
TRADD antibody LS-C500884 is an unconjugated rabbit polyclonal antibody to TRADD from human. It is reactive with human and rat. Validated for ELISA, IF, IHC and WB.
Application
ELISA, IF, IHC, WB
Reactivity
Hu, Rt
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee. ✓
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
Hs.89862 | TRADD
UniProt Number
Q15628
NCBI GenBank
NM_003789 | NP_003780.1
SwissProt
Q15628

Target

Target
Human TRADD
Antigen Species
Human
Epitope
The nuclear form acts as a tumor suppressor by preventing ubiquitination and degradation of isoform p19ARF/ARF of CDKN2A by TRIP12: acts by interacting with TRIP12, leading to disrupt interaction between TRIP12 and isoform p19ARF/ARF of CDKN2A (By similarity). Adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interaction with FADD. Overexpression of TRADD leads to two major TNF-induced responses, apoptosis and activation of NF-kappa-B.
Gene Name
TRADD

Antibody

Host Species
Rabbit
Clonality
Polyclonal
Isotype
IgG

Immunogen

Immunogen
Recombinant Human Tumor necrosis factor receptor type 1-associated DEATH domain protein protein (1-312AA)
Immunogen Type
Recombinant Immunogen

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Preservative
Yes
Purification Method
Protein G Affinity

Storage & Handling

Storage Conditions
Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.
Recommended Storage Buffer
PBS

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