LSBio
Polyclonal Rabbit anti-Human SORCS2 Antibody (aa712-786, IHC, IF)

Immunohistochemistry of paraffin-embedded human brain tissue using SORCS2 Antibody at dilution of 1:100

Polyclonal Rabbit anti-Human SORCS2 Antibody (aa712-786, IHC, IF)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Enzyme-Linked Immunosorbent Assay, Immunofluorescence, Immunohistochemistry (general)
Reactivity:Human
Format:Liquid
See all Human SORCS2 antibodies →
$300.00each
Catalog Number: LS-C501334-50

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Overview

Description
SORCS2 antibody LS-C501334 is an unconjugated rabbit polyclonal antibody to human SORCS2 (aa712-786). Validated for ELISA, IF and IHC. Cited in 2 publications.
Application
ELISA, IF, IHC
Reactivity
Hu
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
KIAA1329 | SORCS2 | VPS10 domain receptor protein
UniProt Number
Q96PQ0
SwissProt
Q96PQ0

Target

Target
Human SORCS2
Antigen Species
Human
Epitope
membrane, neuropeptide receptor activity, neuropeptide signaling pathway
Gene Name
SORCS2

Antibody

Host Species
Rabbit
Clonality
Polyclonal
Isotype
IgG

Immunogen

Immunogen
Recombinant Human VPS10 domain-containing receptor SorCS2 protein (712-786AA)
Immunogen Type
Recombinant Immunogen

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Concentration
3 mg/mL
Preservative
Yes
Purification Method
Protein G Affinity

Storage & Handling

Storage Conditions
Short term: store at -20°C. Long term: store at -80°C. Avoid freeze-thaw cycles.
Recommended Storage Buffer
PBS

SorCS2 Controls Functional Expression of Amino Acid Transporter EAAT3 and Protects Neurons from Oxidative Stress and Epilepsy-Induced Pathology. Malik AR, Szydlowska K, Nizinska K, Asaro A, van Vliet EA, Popp O, Dittmar G, Fritsche-Guenther R, Kirwan JA, Nykjaer A, Lukasiuk K, Aronica E, Willnow TE. Cell reports. 2019 March;26:2792-2804.

PubMed: 30840898 · PMC: PMC6410498


SorCS2 facilitates release of endostatin from astrocytes and controls post-stroke angiogenesis. Anna R Malik, Janet Lips, Malgorzata Gorniak-Walas, Diede W M Broekaart, Antonino Asaro, Melanie T C Kuffner, Christian J Hoffmann, Majed Kikhia, Monika Dopatka, Philipp Boehm-Sturm, Susanne Mueller, Ulrich Dirnagl, Eleonora Aronica, Christoph Harms, Thomas E Willnow. Glia. 2020 June;68:1304-1316.

PubMed: 31898841

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