LSBio
Polyclonal Rabbit anti-Human SENP1 Antibody (IHC, IF, WB)

Positive WB detected in:Hela whole cell lysate,HL60 whole cell lysate,Jurkat whole cell lysate,Mouse heart tissue,Mouse brain tissue,Mouse spleen tissue,Mouse stomach tissue,Mouse skeletal muscle tissue;All lanes: SENP1 antibody at 2.7ug/ml;Secondary;Goat polyclonal to rabbit IgG at 1/50000 dilution;Predicted band size: 74 kDa;Observed band size: 74,50 kDa;

Polyclonal Rabbit anti-Human SENP1 Antibody (IHC, IF, WB)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Enzyme-Linked Immunosorbent Assay, Immunofluorescence, Immunohistochemistry (general), Western Blot
Reactivity:Human, Mouse
Format:Liquid
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$300.00each
Catalog Number: LS-C502018-50

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Overview

Description
SENP1 antibody LS-C502018 is an unconjugated rabbit polyclonal antibody to SENP1 from human. It is reactive with human and mouse. Validated for ELISA, IF, IHC and WB.
Application
ELISA, IF, IHC, WB
Reactivity
Hu, Ms
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee. ✓
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
Sentrin-specific protease 1 | SENP1 | SuPr-2
UniProt Number
Q9P0U3
NCBI GenBank
NM_014554 | NP_055369.1
SwissProt
Q9P0U3

Target

Target
Human SENP1
Antigen Species
Human
Epitope
Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. Deconjugates SUMO1 from HIPK2. Deconjugates SUMO1 from HDAC1 and BHLHE40/DEC1, which decreases its transcriptional repression activity. Deconjugates SUMO1 from CLOCK, which decreases its transcriptional activation activity. Deconjugates SUMO2 from MTA1. Desumoylates CCAR2 which decreases its interaction with SIRT1 (PubMed:25406032).
Gene Name
SENP1

Antibody

Host Species
Rabbit
Clonality
Polyclonal
Isotype
IgG

Immunogen

Immunogen
Recombinant Human Sentrin-specific protease 1 protein (63-214AA)
Immunogen Type
Recombinant Immunogen

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Preservative
Yes
Purification Method
Protein G Affinity

Storage & Handling

Storage Conditions
Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.
Recommended Storage Buffer
PBS

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