LSBio
Polyclonal Rabbit anti-Human RB1CC1 / CC1 Antibody (HRP)

Polyclonal Rabbit anti-Human RB1CC1 / CC1 Antibody (HRP)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Enzyme-Linked Immunosorbent Assay
Reactivity:Human
Format:Liquid
See all Human RB1CC1 / CC1 antibodies →
$300.00each
Catalog Number: LS-C501595-50

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Overview

Description
CC1 antibody LS-C501595 is an HRP-conjugated rabbit polyclonal antibody to human CC1 (RB1CC1). Validated for ELISA.
Application
ELISA
Reactivity
Hu
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee. ✓
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
CC1 | DRAGOU14 | FIP200 | RBICC | RB1CC1 | KIAA0203 | RB1-inducible coiled-coil 1
UniProt Number
Q8TDY2
NCBI GenBank
NM_014781 | NP_055596.3
SwissProt
Q8TDY2

Target

Target
Human RB1CC1 / CC1
Antigen Species
Human
Epitope
Plays a role as a modulator of TGF-beta-signaling by restricting substrate specificity of RNF111. Involved in autophagy. Regulates early events but also late events of autophagosome formation through direct interaction with Atg16L1. Required for the formation of the autophagosome-like double-membrane structure that surrounds the Salmonella-containing vacuole (SCV) duting S.typhimurium infection and subsequent xenophagy. Autophagy positively regulates repair of DNA damage induced by ionizing radiation and negatively regulates apoptosis. Plays an indispensible role in fetal hematopoiesis and in the regulation of neuronal homeostasis (By similarity). Implicated in the regulation of RB1 expression. Functions as a DNA-binding transcription factor. Is a potent regulator of the RB1 pathway and a mediator that plays a crucial role in muscular differentiation. Expression is, thus, a prerequisite for myogenic differentiation. Inhibits PTK2/FAK1 and PTK2B/PYK2 activity and activation of downstream signaling pathways.
Gene Name
RB1CC1

Antibody

Host Species
Rabbit
Clonality
Polyclonal
Isotype
IgG

Immunogen

Immunogen
Recombinant Human RB1-inducible coiled-coil protein 1 protein (1544-1594AA)
Immunogen Type
Recombinant Immunogen

Format

Conjugate/Label
Horseradish Peroxidase
Format
Liquid
Formulation
PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Preservative
Yes
Purification Method
Protein G Affinity

Storage & Handling

Storage Conditions
Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.
Recommended Storage Buffer
PBS

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