LSBio
Polyclonal Rabbit anti-Human PQBP1 Antibody (Biotin)

Polyclonal Rabbit anti-Human PQBP1 Antibody (Biotin)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Enzyme-Linked Immunosorbent Assay
Reactivity:Human
Format:Liquid
See all Human PQBP1 antibodies →
$300.00each
Catalog Number: LS-C499582-50

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Overview

Description
PQBP1 antibody LS-C499582 is a biotin-conjugated rabbit polyclonal antibody to human PQBP1. Validated for ELISA.
Application
ELISA
Reactivity
Hu
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee. ✓
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
MRX55 | MRXS3 | PQBP-1 | PQBP1 | MRXS8 | NPW38 | RENS1 | SHS
UniProt Number
O60828
NCBI GenBank
NM_005710 | NP_005701.1
SwissProt
O60828

Target

Target
Human PQBP1
Antigen Species
Human
Epitope
Probably functions as scaffold protein that is part of numerous complexes and thereby plays a role in pre-mRNA splicing, transcription regulation and neuron development. Required for normal alternative splicing of target pre-mRNA species (PubMed:23512658). May suppress the ability of POU3F2 to transactivate the DRD1 gene in a POU3F2 dependent manner. Can activate transcription directly or via association with the transcription machinery. May be involved in ATXN1 mutant-induced cell death. The interaction with ATXN1 mutant reduces levels of phosphorylated RNA polymerase II large subunit.
Gene Name
PQBP1

Antibody

Host Species
Rabbit
Clonality
Polyclonal
Isotype
IgG

Immunogen

Immunogen
Recombinant Human Polyglutamine-binding protein 1 protein (2-265AA)
Immunogen Type
Recombinant Immunogen

Format

Conjugate/Label
Biotin
Format
Liquid
Formulation
PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Preservative
Yes
Purification Method
Protein G Affinity

Storage & Handling

Storage Conditions
Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.
Recommended Storage Buffer
PBS

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