LSBio
Polyclonal Rabbit anti-Human PHLDA3 Antibody (IHC)

Human, liver: Formalin-Fixed, Paraffin-Embedded (FFPE)

Polyclonal Rabbit anti-Human PHLDA3 Antibody (IHC)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Enzyme-Linked Immunosorbent Assay, Immunohistochemistry, Paraffin
Reactivity:Human
Format:Liquid
See all Human PHLDA3 antibodies →
$300.00each
Catalog Number: LS-C499531-50

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Overview

Description
PHLDA3 antibody LS-C499531 is an unconjugated rabbit polyclonal antibody to human PHLDA3. Validated for ELISA and IHC.
Application
ELISA, IHC-P
Reactivity
Hu
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee. ✓
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
PHLDA3 | TIH1 | TDAG51/Ipl homolog 1
Recommended Dilution: IHC-P
1:50 - 1:200
UniProt Number
Q9Y5J5
NCBI GenBank
NM_012396 | NP_036528.1
SwissProt
Q9Y5J5

Target

Target
Human PHLDA3
Antigen Species
Human
Epitope
p53/TP53-regulated repressor of Akt/AKT1 signaling. Represses AKT1 by preventing AKT1-binding to membrane lipids, thereby inhibiting AKT1 translocation to the cellular membrane and activation. Contributes to p53/TP53-dependent apoptosis by repressing AKT1 activity. Its direct transcription regulation by p53/TP53 may explain how p53/TP53 can negatively regulate AKT1. May act as a tumor suppressor.
Gene Name
PHLDA3

Antibody

Host Species
Rabbit
Clonality
Polyclonal
Isotype
IgG

Immunogen

Immunogen
Recombinant Human Pleckstrin homology-like domain family A member 3 protein (43-95AA)
Immunogen Type
Recombinant Immunogen

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Concentration
5 mg/mL
Preservative
Yes
Purification Method
Protein G Affinity

Storage & Handling

Storage Conditions
Short term: store at -20°C. Long term: store at -80°C. Avoid freeze-thaw cycles.
Recommended Storage Buffer
PBS

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