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Polyclonal Rabbit anti-Human PECAM-1 / CD31 Antibody (IF)

Polyclonal Rabbit anti-Human PECAM-1 / CD31 Antibody (IF)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Immunofluorescence
Reactivity:Human, Mouse, Rat
Format:Liquid
See all Human PECAM-1 / CD31 antibodies →
$490.00each
Catalog Number: LS-C415608-0.1

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Overview

Description
CD31 antibody LS-C415608 is an unconjugated rabbit polyclonal antibody to CD31 (PECAM-1) from human. It is reactive with human, mouse and rat. Validated for IF.
Application
IF
Reactivity
Hu, Ms, Rt
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee. ✓
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
CD31 | CD31 antigen | EndoCAM | PECA1 | PECAM1 | PECAM-1 | GPIIA
Recommended Dilution: IF/ICC
1:20 - 1:100
UniProt Number
P16284
NCBI GenBank
NM_000442 | NP_000433.4
SwissProt
P16284

Target

Target
Human PECAM-1 / CD31
Antigen Species
Human
Epitope
CD31 (PECAM1) is a member of the immunoglobulin (Ig) superfamily that is expressed on the surface of circulating platelets, monocytes, neutrophils, and particular T-cell subsets. CD31 is also a major constituent of the endothelial cell intercellular junction, where up to an estimated 1 million molecules are concentrated. Because of this cellular expression pattern, CD31 is implicated in several functions, including transendothelial migration of leukocytes, angiogenesis, and integrin activation. Ig superfamily members are known to mediate cell adhesion, or antigen recognition, e.g. immunoglobulins, T-cell receptors, and MHC molecules. In addition, a subgroup comprising 30 members characterized by the presence of one or more immunoreceptor tyrosine-based inhibitory motifs (ITIMs) within their cytoplasmic domain has also been recognized. CD31, which has 6 ITIMs within its cytoplasmic domain, is a member of this subfamily.
Gene Name
PECAM1

Antibody

Host Species
Rabbit
Clonality
Polyclonal

Immunogen

Immunogen
KLH-conjugated synthetic peptide from the N-Terminus of human PECAM1.
Immunogen Type
Synthetic Peptide (Linear)

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, pH 7.4, 0.09% Sodium Azide, 1% BSA
Preservative
Yes
Purification Method
Protein G Affinity

Storage & Handling

Storage Conditions
Store at 4°C.
Recommended Storage Buffer
PBS

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