LSBio
Polyclonal Rabbit anti-Human NR1H3 / LXR Alpha Antibody (C-Terminus, IHC, WB)

Anti-NR1H3 / LXR Alpha antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Polyclonal Rabbit anti-Human NR1H3 / LXR Alpha Antibody (C-Terminus, IHC, WB)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot
Reactivity:Human, Mouse
Format:Liquid
See all NR1H3 / LXR Alpha antibodies →
$470.00each
Catalog Number: LS-B3526-50

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Overview

Description
LXR Alpha antibody LS-B3526 is an unconjugated rabbit polyclonal antibody to LXR Alpha (NR1H3) (C-Terminus) from human. It is reactive with human and mouse. Validated for IHC and WB. Cited in 2 publications.
Application
IHC, IHC-P, WB
Reactivity
Hu, Ms
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
Liver X receptor alpha | LXRA | LXR-a | Oxysterols receptor LXR-alpha | LXR alpha | NR1H3 | Lxralpha | RLD-1
Recommended Dilution: IHC-P
5 µg/ml
UniProt Number
Q13133
SwissProt
Q13133

Target

Target
NR1H3 / LXR Alpha
Antigen Species
Human
Specificity
Human NR1H3 / LXR Alpha
Epitope
Human NR1H3 / LXR Alpha
Gene Name
NR1H3

Antibody

Host Species
Rabbit
Clonality
Polyclonal
Origin Species
Human

Immunogen

Immunogen
Synthetic peptide from C-Terminus of human NR1H3 (Q13133, NP_005684). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Galago, Marmoset, Mouse, Rat, Goat, Hamster, Elephant, Panda, Dog, Bovine, Bat, Rabbit, Horse, Pig, Guinea pig, Turkey, Zebra finch, Chicken, Platypus, Lizard, Xenopus, Trout, Salmon, Stickleback, Zebrafish (100%).
Immunogen Type
Synthetic Peptide (Linear)

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, 0.09% sodium azide, 2% sucrose
Concentration
0.5 mg/mL
Volume
50 Microliter
Animal Free
No
Carrier-Free
Yes
Preservative
Yes
Purification Method
Affinity Purified

Storage & Handling

Storage Conditions
Short term: Store at 2-8°C. Long term: Aliquot and store at -20°C. Avoid freeze/thaw cycles.
Recommended Storage Buffer
PBS

Protective effects of farnesoid X receptor (FXR) on hepatic lipid accumulation are mediated by hepatic FXR and independent of intestinal FGF15 signal. Schmitt J, Kong B, Stieger B, Tschopp O, Schultze SM, Rau M, Weber A, M[Character fc]llhaupt B, Guo GL, Geier A. Liver international : official journal of the International Association for the Study of the Liver. Apr;35:1133-44.

PubMed: 25156247 · PMC: PMC4146754


Foam Cell Formation In Vivo Converts Macrophages to a Pro-Fibrotic Phenotype. Thomas AC, Eijgelaar WJ, Daemen MJ, Newby AC. PloS one. 2015;10:e0128163.

PubMed: 26197235 · PMC: PMC4510387

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