Polyclonal Rabbit anti-Human SLC5A11 / SMIT2 Antibody (WB)
Catalog Number: LS-C748223
2 sizes / from $281.00
Antibody: Rabbit Polyclonal
Applications: Immunohistochemistry (general), Western Blot
Reactivity: Human, Mouse, Rat
Format: Liquid
Immunofluorescence of paraformaldehyde-fixed HeLa, using NPR-A antibody at 1:200 dilution.
Polyclonal Rabbit anti-Human NPRA / NPR1 Antibody (IHC, IF, WB)
Primary AntibodyLSBio Guarantee
| Antibody: | Rabbit Polyclonal |
| Applications: | Immunocytochemistry, Immunofluorescence, Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot |
| Reactivity: | Human, Rat |
| Format: | Liquid |
$459.00each
Catalog Number: LS-C109432-100
Catalog Number: LS-C109432
For bulk orders or custom formulations:
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- Description
- NPR1 antibody LS-C109432 is an unconjugated rabbit polyclonal antibody to NPR1 (NPRA) from human. It is reactive with human and rat. Validated for ICC, IF, IHC and WB. Cited in 2 publications.
- Application
- ICC, IF, IHC, IHC-P, WB
- Reactivity
- Hu, Rt
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Polyclonal Antibodies
- Alternative Names
- ANPR-A | ANPa | Guanylate cyclase A | GUCY2A | GC-A | GUC2A | Natriuretic peptide receptor A | NPRA | Natriuretic peptide receptor 1 | NPPA receptor | NPR1 | ANP-A | ANPRA | NPR-A
- Recommended Dilution: IF/ICC
- 1:100 - 1:200
- Recommended Dilution: WB
- 1:500 - 1:3000
- UniProt Number
- P16066
- NCBI GenBank
- NM_000906 | NP_000897.3
- SwissProt
- P16066
Target
- Target
- Human NPRA / NPR1
- Antigen Species
- Human
- Epitope
- Human NPR-A.
- Gene Name
- NPR1
Antibody
- Host Species
- Rabbit
- Clonality
- Polyclonal
Immunogen
- Immunogen
- Recombinant protein encompassing a sequence within the center region of human NPR-A. The exact sequence is proprietary.
- Immunogen Type
- Recombinant Immunogen
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- 1X PBS, pH 7, 0.025% ProClin™ 300, 20% Glycerol
- Concentration
- 0.5 mg/mL
- Volume
- 100 Microliter
- Preservative
- Yes
- Purification Method
- Affinity Purified
Storage & Handling
- Storage Conditions
- Short term: store at 4°C. Long term: store at -20°C. Avoid freeze-thaw cycles.
- Recommended Storage Buffer
- 1X PBS
B-type natriuretic peptide is neither itch-specific nor functions upstream of the GRP-GRPR signaling pathway. Liu XY, Wan L, Huo FQ, Barry DM, Li H, Zhao ZQ, Chen ZF. Molecular pain. 2014;10:4.
PubMed: 24438367 · PMC: PMC3930899
Therapeutic antibody targeting natriuretic peptide receptor 1 inhibits gastric cancer growth via BCL-2-mediated intrinsic apoptosis. Masahiro Sasahara, Mitsuro Kanda, Chie Tanaka, Dai Shimizu, Shinichi Umeda, Hideki Takami, Yoshikuni Inokawa, Norifumi Hattori, Masamichi Hayashi, Goro Nakayama, Yasuhiro Kodera. International journal of cancer. Journal international du cancer. 2024 April;154:1272-1284.
PubMed: 38151776
