LSBio
Polyclonal Rabbit anti-Human MKX Antibody (aa191-240, IHC, WB)

Anti-MKX antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 2.5-5 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Polyclonal Rabbit anti-Human MKX Antibody (aa191-240, IHC, WB)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot
Reactivity:Human
Format:Liquid
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$470.00each
Catalog Number: LS-B8063-50

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Overview

Description
MKX antibody LS-B8063 is an unconjugated rabbit polyclonal antibody to human MKX (aa191-240). Validated for IHC and WB. Cited in 3 publications.
Application
IHC, IHC-P, WB
Reactivity
Hu
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
Homeobox protein Mohawk | IFRX | MKX | Mohawk homeobox | C10orf48 | IRXL1
Recommended Dilution: IHC-P
2.5 - 5 µg/ml
Recommended Dilution: WB
0.2 - 1 µg/ml
UniProt Number
Q8IYA7
SwissProt
Q8IYA7

Target

Target
MKX
Antigen Species
Human
Specificity
aa191-240 of human MKX
Epitope
Human MKX
Gene Name
MKX

Antibody

Host Species
Rabbit
Clonality
Polyclonal
Origin Species
Human

Immunogen

Immunogen
Synthetic peptide located between aa191-240 of human MKX (Q8IYA7, NP_775847). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Marmoset (100%); Galago, Mouse, Rat, Hamster, Dog, Bovine, Bat, Rabbit, Horse, Opossum, Guinea pig, Zebra finch, Platypus, Lizard, Xenopus, Seabass, Stickleback (92%); Elephant (85%); Turkey, Chicken, Zebrafish (84%).
Immunogen Type
Synthetic Peptide (Linear)

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, 0.09% sodium azide, 2% sucrose
Concentration
0.5 mg/mL
Volume
50 Microliter
Animal Free
No
Carrier-Free
Yes
Preservative
Yes
Purification Method
Affinity Purified

Storage & Handling

Storage Conditions
Short term: Store at 2-8°C. Long term: Aliquot and store at -20°C. Avoid freeze/thaw cycles.
Recommended Storage Buffer
PBS

Transcription factor Mohawk and the pathogenesis of human anterior cruciate ligament degradation. Nakahara H, Hasegawa A, Otabe K, Ayabe F, Matsukawa T, Onizuka N, Ito Y, Ozaki T, Lotz MK, Asahara H. Arthritis and rheumatism. 2013 Aug;65:2081-9.

PubMed: 23686683 · PMC: PMC3840305


Mohawk promotes the tenogenesis of mesenchymal stem cells through activation of the TGF beta signaling pathway. Liu H, Zhang C, Zhu S, Lu P, Zhu T, Gong X, Zhang Z, Hu J, Yin Z, Heng BC, Chen X, Wei Ouyang H. Stem cells (Dayton, Ohio). Feb;33:443-55.

PubMed: 25332192


Osteocalcin expressing cells from tendon sheaths in mice contribute to tendon repair by activating Hedgehog signaling. Wang Y, Zhang X, Huang H, Xia Y, Yao Y, Mak AF, Yung PS, Chan KM, Wang L, Zhang C, Huang Y, Mak KK. eLife. 2017;6.

PubMed: 29244023

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