Polyclonal Rabbit anti-Human SLC5A11 / SMIT2 Antibody (WB)
Catalog Number: LS-C748223
2 sizes / from $281.00
Antibody: Rabbit Polyclonal
Applications: Immunohistochemistry (general), Western Blot
Reactivity: Human, Mouse, Rat
Format: Liquid
WB of LPXN / Leupaxin antibody. Lane 1: Rat Thymus Tissue Lysate. Lane 2: JURKAT Cell Lysate.
Polyclonal Rabbit anti-Human LPXN / Leupaxin Antibody (aa115-129, IHC, WB)
Primary AntibodyLSBio Guarantee
| Antibody: | Rabbit Polyclonal |
| Applications: | Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot |
| Reactivity: | Human, Mouse, Non-Human Primate, Rat |
| Format: | Lyophilized |
$480.00each
Catalog Number: LS-C313296-100
Catalog Number: LS-C313296
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- Description
- Leupaxin antibody LS-C313296 is an unconjugated rabbit polyclonal antibody to Leupaxin (LPXN) (aa115-129) from human. It is reactive with human, mouse, rat and other species. Validated for IHC and WB. Cited in 1 publication.
- Application
- IHC, IHC-P, WB
- Reactivity
- Hu, Ms, NHP, Rt
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Polyclonal Antibodies
- Alternative Names
- LDLP | Leupaxin | LDPL | LPXN
- UniProt Number
- O60711
- NCBI GenBank
- NM_004811 | NP_004802.1
- SwissProt
- O60711
Target
- Target
- Human LPXN / Leupaxin
- Antigen Species
- Human
- Epitope
- Macrophages, monocytes and osteoclasts (at protein level). Strongly expressed in cells and tissues of hematopoietic origin. Highest expression in lymphoid tissues such as spleen, lymph node, thymus and appendix and in the vascular smooth muscle. Lower levels in bone marrow and fetal liver. Also expressed in peripheral blood lymphocytes and a number of hematopoietic cell lines. Very low levels found in epithelial cell lines. Expressed in prostate cancer (PCa) cells and its expression intensity is directly linked to PCa progression. .
- Gene Name
- LPXN
Antibody
- Host Species
- Rabbit
- Clonality
- Polyclonal
Immunogen
- Immunogen
- A synthetic peptide corresponding to a sequence at the N-Terminus of human Leupaxin(115-129 aa KKHLPDKQDHKASLD), different from the related rat sequence by two amino acids, and from the related mouse sequence by three amino acids.
- Immunogen Type
- Synthetic Peptide (Linear)
Format
- Conjugate/Label
- Unconjugated
- Format
- Lyophilized
- Formulation
- Lyophilized from 0.2mg Na2HPO4, 5mg BSA, 0.9mg NaCl, 0.05mg Thimerosal, 0.05mg sodium azide.
- Preservative
- Yes
- Purification Method
- Affinity Purified
Storage & Handling
- Storage Conditions
- At -20°C for 1 year. After reconstitution, at 4°C for 1 month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid freeze-thaw cycles.
- Recommended Storage Buffer
- NaCl
Protein tyrosine kinase 2b inhibition reverts niche-associated resistance to tyrosine kinase inhibitors in AML. Catana Allert, Alexander Waclawiczek , Sarah Miriam Naomi Zimmermann , Stefanie Göllner, Daniel Heid, Maike Janssen, Simon Renders, Christian Rohde, Marcus Bauer, Margarita Bruckmann, Rafael Zinz, Cornelius Pauli, Birgit Besenbeck, Claudia Wickenhauser, Andreas Trumpp, Jeroen Krijgsveld, Carsten Müller-Tidow, Maximilian Felix Blank. Leukemia. 2022 October;36:2418-2429. PubMed: 36056084 PMC: PMC9522596
