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Polyclonal Rabbit anti-Human KMT2A / MLL Antibody (N-Terminus, IHC, WB)

WB Analysis: Samples: Nuclear extract (50 ug for WT and KO; 10 ug for EF, EN and EC) from 293T cells that were transfected with MLL1 C-terminal 180 kD fragment (EC), 293T cells transfected with N-terminally truncated MLL1 fragment (EN; N300-tr), 293T cells transfected with MLL1 N-terminal 300 kD fragment (EF), MLL1 +/+ mouse embryonic stem cells (WT), and MLL1 -/- embryonic stem cells (KO). Antibody used at the indicated concentrations. Detection: One second exposure with chemiluminescence.

Polyclonal Rabbit anti-Human KMT2A / MLL Antibody (N-Terminus, IHC, WB)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot
Reactivity:Human, Mouse
Format:Liquid
See all Human KMT2A / MLL antibodies →
$966.00each
Catalog Number: LS-C72739-100

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Overview

Description
MLL antibody LS-C72739 is an unconjugated rabbit polyclonal antibody to MLL (KMT2A) (N-Terminus) from human. It is reactive with human and mouse. Validated for IHC and WB.
Application
IHC, IHC-P, WB
Reactivity
Hu, Ms
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee. ✓
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
ALL1 | CDK6/MLL fusion protein | FLJ11783 | HRX | HTRX | HTRX1 | KMT2A | Lysine N-methyltransferase 2A | MLL1A | MLL/GAS7 | MLL1 | ALL-1 | MLL | MLL/GAS7 fusion protein | TRX1 | WDSTS | Trithorax-like protein | Zinc finger protein HRX | CXXC7 | MLL-AF4 der(11) fusion protein | MLL/GMPS fusion protein | TET1-MLL
UniProt Number
Q03164
NCBI GenBank
NM_005933 | NP_005924.2
SwissProt
Q03164

Target

Target
Human KMT2A / MLL
Antigen Species
Human
Epitope
Specific for human MLL1 protein. Species cross-reactivity: mouse. Other species have not been tested.
Gene Name
KMT2A

Antibody

Host Species
Rabbit
Clonality
Polyclonal

Immunogen

Immunogen
A synthetic peptide mapping to a region between residues 720 and 780 of human myeloid/lymphoid or mixed-lineage leukemia 1 using the number given in Swiss-Prot entry Q03164 (GeneID 4297). The epitope is found in the N-Terminus 300 kDa fragment generated by proteolytic cleavage. The epitope is found in isoform 14P-18B of MLL1.
Immunogen Type
Synthetic Peptide (Linear)

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
Tris-citrate/phosphate, pH 7.5, 0.09% sodium azide.
Concentration
1 mg/mL
Volume
100 Microliter
Preservative
Yes
Purification Method
Affinity Purified

Storage & Handling

Storage Conditions
Short term: store at 4°C. Long term: aliquot and store at -20°C. Avoid freeze-thaw cycles.
Recommended Storage Buffer
Tris-citrate

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