Polyclonal Rabbit anti-Human SLC5A11 / SMIT2 Antibody (WB)
Catalog Number: LS-C748223
2 sizes / from $281.00
Antibody: Rabbit Polyclonal
Applications: Immunohistochemistry (general), Western Blot
Reactivity: Human, Mouse, Rat
Format: Liquid
HepG2 Cell Lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Polyclonal Rabbit anti-Human HSPB1 / HSP27 Antibody (C-Terminus, IHC, WB)
Primary AntibodyLSBio Guarantee
| Antibody: | Rabbit Polyclonal |
| Applications: | Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot |
| Reactivity: | Human |
| Format: | Liquid |
$405.00each
Catalog Number: LS-C31836-100
Catalog Number: LS-C31836
For bulk orders or custom formulations:
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- Description
- HSP27 antibody LS-C31836 is an unconjugated rabbit polyclonal antibody to human HSP27 (HSPB1) (C-Terminus). Validated for IHC and WB. Cited in 6 publications.
- Application
- IHC, IHC-P, WB
- Reactivity
- Hu
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Polyclonal Antibodies
- Alternative Names
- 28 kDa heat shock protein | Heat shock 27 kDa protein | Heat shock 27kD protein 1 | Heat shock 27kDa protein 1 | HSP27 | HSP28 | HSP 27 | Hsp25 | HSPB1 | SRP27 | Stress-responsive protein 27 | CMT2F | Heat shock 27 kd protein | Heat shock protein beta-1 | HMN2B | HS.76067
- UniProt Number
- P04792
- NCBI GenBank
- NM_001540 | NP_001531.1
- SwissProt
- P04792
Target
- Target
- Human HSPB1 / HSP27
- Antigen Species
- Human
- Epitope
- Human HSPB1
- Gene Name
- HSPB1
Antibody
- Host Species
- Rabbit
- Clonality
- Polyclonal
- Isotype
- IgG
Immunogen
- Immunogen
- Synthetic peptide from C-Terminus of human HSPB1 (P04792, NP_001531). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Monkey (100%); Marmoset (84%).
- Immunogen Type
- Synthetic Peptide (Linear)
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS, 0.09% sodium azide, 2% sucrose
- Concentration
- 0.5 mg/mL
- Volume
- 100 Microliter
- Preservative
- Yes
- Purification Method
- Protein A Affinity
Storage & Handling
- Storage Conditions
- Short term: Store at 2-8°C. Long term: Aliquot and store at -20°C. Avoid freeze/thaw cycles.
- Recommended Storage Buffer
- PBS
Rationally Repurposing Ruxolitinib (Jakafi (®)) as a Solid Tumor Therapeutic. Tavallai M, Booth L, Roberts JL, Poklepovic A, Dent P. Frontiers in oncology. 2016;6:142.
PubMed: 27379204 · PMC: PMC4904019
Multi-kinase inhibitors can associate with heat shock proteins through their NH2-termini by which they suppress chaperone function. Booth L, Shuch B, Albers T, Roberts JL, Tavallai M, Proniuk S, Zukiwski A, Wang D, Chen CS, Bottaro D, Ecroyd H, Lebedyeva IO, Dent P. Oncotarget. 2016;7:12975-96.
PubMed: 26887051 · PMC: PMC4914336
[Pemetrexed + Sorafenib] lethality is increased by inhibition of ERBB1/2/3-PI3K-NF?B compensatory survival signaling. Booth L, Roberts JL, Tavallai M, Chuckalovcak J, Stringer DK, Koromilas AE, Boone DL, McGuire WP, Poklepovic A, Dent P. Oncotarget. 2016;7:23608-32.
PubMed: 27015562 · PMC: PMC5029651
Multi-kinase inhibitors interact with sildenafil and ERBB1/2/4 inhibitors to kill tumor cells in vitro and in vivo. Booth L, Albers T, Roberts JL, Tavallai M, Poklepovic A, Lebedyeva IO, Dent P. Oncotarget. 2016;7:40398-40417.
PubMed: 27259258 · PMC: PMC5130016
PDE5 inhibitors enhance the lethality of pemetrexed through inhibition of multiple chaperone proteins and via the actions of cyclic GMP and nitric oxide. Booth L, Roberts JL, Poklepovic A, Gordon S, Dent P. Oncotarget. 2017;8:1449-1468.
PubMed: 27903966 · PMC: PMC5352068
The HDAC inhibitor AR42 interacts with pazopanib to kill trametinib/dabrafenib-resistant melanoma cells in vitro and in vivo. Booth L, Roberts JL, Sander C, Lee J, Kirkwood JM, Poklepovic A, Dent P. Oncotarget. 2017;8:16367-16386.
PubMed: 28146421 · PMC: PMC5369969
