LSBio
Polyclonal Rabbit anti-Human GUCY1B2 Antibody (N-Terminal, IHC)

Polyclonal Rabbit anti-Human GUCY1B2 Antibody (N-Terminal, IHC)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Enzyme-Linked Immunosorbent Assay, Immunohistochemistry (general)
Reactivity:Human, Mouse, Rat
Format:Liquid
See all Human GUCY1B2 antibodies →
$301.00each
Catalog Number: LS-C383668-50

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Overview

Description
GUCY1B2 antibody LS-C383668 is an unconjugated rabbit polyclonal antibody to GUCY1B2 (N-Terminal) from human. It is reactive with human, mouse and rat. Validated for ELISA and IHC. Cited in 1 publication.
Application
ELISA, IHC
Reactivity
Hu, Ms, Rt
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
GC-SB2 | GCS-beta-2 | GUCY1B2 | Guanylate cyclase
Recommended Dilution: ELISA
1:10000
Recommended Dilution: IHC
1:100 - 1:300
UniProt Number
O75343
SwissProt
O75343

Target

Target
Human GUCY1B2
Antigen Species
Human
Epitope
GCS-beta-2 Polyclonal Antibody detects endogenous levels of GCS-beta-2 protein.

Antibody

Host Species
Rabbit
Clonality
Polyclonal
Isotype
IgG

Immunogen

Immunogen
Synthesized peptide derived from human GCS-beta-2.
Immunogen Type
Synthetic Peptide (Linear)

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, 0.02% Sodium Azide, 50% Glycerol, 0.5% BSA
Preservative
Yes
Purification Method
Affinity Purified

Storage & Handling

Storage Conditions
Store at -20°C. Avoid freeze-thaw cycles.
Recommended Storage Buffer
PBS
Stimulation of soluble guanylate cyclase exerts antiinflammatory actions in the liver through a VASP/NF-?B/NLRP3 inflammasome circuit. Roger Flores-Costa, Marta Duran-Güell, Mireia Casulleras, Cristina López-Vicario, José Alcaraz-Quiles, Alba Diaz, Juan J Lozano, Esther Titos, Katherine Hall, Renee Sarno, Jaime L Masferrer, Joan Clària. Proceedings of the National Academy of Sciences of the United States of America. 2020 November;117:28263-28274. PubMed: 33106416 PMC: PMC7668051

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