LSBio
Polyclonal Rabbit anti-Human GCGR / Glucagon Receptor Antibody (aa26-136, IHC, IF, WB)

Positive WB detected in:Mouse heart tissue,Mouse lung tissue,Mouse kidney tissue;All lanes: Gcgr antibody at 3ug/ml;Secondary;Goat polyclonal to rabbit IgG at 1/50000 dilution;Predicted band size: 55 kDa;Observed band size: 55 kDa;

Polyclonal Rabbit anti-Human GCGR / Glucagon Receptor Antibody (aa26-136, IHC, IF, WB)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Enzyme-Linked Immunosorbent Assay, Immunofluorescence, Immunohistochemistry (general), Western Blot
Reactivity:Human, Mouse
Format:Liquid
See all Human GCGR / Glucagon Receptor antibodies →
$300.00each
Catalog Number: LS-C498919-50

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Overview

Description
Glucagon Receptor antibody LS-C498919 is an unconjugated rabbit polyclonal antibody to Glucagon Receptor (GCGR) (aa26-136) from human. It is reactive with human and mouse. Validated for ELISA, IF, IHC and WB.
Application
ELISA, IF, IHC, WB
Reactivity
Hu, Ms
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee. ✓
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
GL-R | GCGR | Glucagon receptor | GGR
UniProt Number
P47871
SwissProt
P47871

Target

Target
Human GCGR / Glucagon Receptor
Antigen Species
Human
Epitope
G-protein coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis. Regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and gluconeogenesis. Plays an important role in mediating the responses to fasting. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Promotes activation of adenylate cyclase. Besides, plays a role in signaling via a phosphatidylinositol-calcium second messenger system.
Gene Name
GCGR

Antibody

Host Species
Rabbit
Clonality
Polyclonal
Isotype
IgG

Immunogen

Immunogen
Recombinant Human Glucagon receptor protein (26-136AA)
Immunogen Type
Recombinant Immunogen

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Preservative
Yes
Purification Method
Protein G Affinity

Storage & Handling

Storage Conditions
Short term: store at -20°C. Long term: store at -80°C. Avoid freeze-thaw cycles.
Recommended Storage Buffer
PBS

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