LSBio
Polyclonal Rabbit anti-Human FBXO3 Antibody (Biotin)

Polyclonal Rabbit anti-Human FBXO3 Antibody (Biotin)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Enzyme-Linked Immunosorbent Assay
Reactivity:Human
Format:Liquid
See all Human FBXO3 Antibodies →
$300.00each
Catalog Number: LS-C502147-50

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Overview

Description
FBXO3 antibody LS-C502147 is a biotin-conjugated rabbit polyclonal antibody to human FBXO3. Validated for ELISA.
Application
ELISA
Reactivity
Hu
Intended Use
RUO
Guarantees
This antibody carries the LSBio 100% Guarantee. ✓
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
F-box protein 3 | F-box protein FBX3 | FBXO3 | F-box only protein 3 | FBA | FBX3
UniProt Number
Q9UK99
NCBI GenBank
NM_012175, NP_036307.2
SwissProt
Q9UK99

Target

Target
Human FBXO3
Antigen Species
Hu
Epitope
Substrate recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Mediates the ubiquitination of HIPK2 and probably that of EP300, leading to rapid degradation by the proteasome. In the presence of PML, HIPK2 ubiquitination still occurs, but degradation is prevented. PML, HIPK2 and FBXO3 may act synergically to activate p53/TP53-dependent transactivation.
Gene Name
FBXO3

Antibody

Host Species
Rb
Clonality
Polyclonal
Isotype
IgG

Immunogen

Immunogen
Recombinant Human F-box only protein 3 protein (276-376AA)
Immunogen Type
Recom

Format

Conjugate/Label
Biotin
Format
Liquid
Formulation
PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Preservative
Yes
Purification Method
Prot G

Storage & Handling

Storage Conditions
Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.
Recommended Storage Buffer
PBS

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