LSBio
Polyclonal Rabbit anti-Human DEPDC2 Antibody (IHC, IF, WB)

Positive WB detected in:Mouse brain tissue;All lanes: PREX2 antibody at 3.4ug/ml;Secondary;Goat polyclonal to rabbit IgG at 1/50000 dilution;Predicted band size: 183,172,113 kDa;Observed band size: 183,113 kDa;

Polyclonal Rabbit anti-Human DEPDC2 Antibody (IHC, IF, WB)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Enzyme-Linked Immunosorbent Assay, Immunofluorescence, Immunohistochemistry (general), Western Blot
Reactivity:Human, Mouse
Format:Liquid
See all Human DEPDC2 antibodies →
$300.00each
Catalog Number: LS-C501085-50

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Overview

Description
DEPDC2 antibody LS-C501085 is an unconjugated rabbit polyclonal antibody to DEPDC2 from human. It is reactive with human and mouse. Validated for ELISA, IF, IHC and WB.
Application
ELISA, IF, IHC, WB
Reactivity
Hu, Ms
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee. ✓
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
DEP domain containing 2 | DEP.2 | DEPDC2 | P-REX2 | PREX2
UniProt Number
Q70Z35
NCBI GenBank
NM_025170 | NP_079446.3
SwissProt
Q70Z35

Target

Target
Human DEPDC2
Antigen Species
Human
Epitope
Functions as a RAC1 guanine nucleotide exchange factor (GEF), activating Rac proteins by exchanging bound GDP for free GTP. Its activity is synergistically activated by phosphatidylinositol 3,4,5-trisphosphate and the beta gamma subunits of heterotrimeric G protein. Mediates the activation of RAC1 in a PI3K-dependent manner. May be an important mediator of Rac signaling, acting directly downstream of both G protein-coupled receptors and phosphoinositide 3-kinase.
Gene Name
PREX2

Antibody

Host Species
Rabbit
Clonality
Polyclonal
Isotype
IgG

Immunogen

Immunogen
Recombinant human Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein (1417-1592AA)
Immunogen Type
Recombinant Immunogen

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Concentration
2.5 mg/mL
Preservative
Yes
Purification Method
Protein G Affinity

Storage & Handling

Storage Conditions
Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.
Recommended Storage Buffer
PBS

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