LSBio
Polyclonal Rabbit anti-Human CYP1A2 Antibody (IHC, WB)

Polyclonal Rabbit anti-Human CYP1A2 Antibody (IHC, WB)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Enzyme-Linked Immunosorbent Assay, Immunohistochemistry (general), Western Blot
Reactivity:Human
Format:Liquid
See all Human CYP1A2 antibodies →
$402.00each
Catalog Number: LS-C415674-0.1

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Overview

Description
CYP1A2 antibody LS-C415674 is an unconjugated rabbit polyclonal antibody to human CYP1A2. Validated for ELISA, IHC and WB.
Application
ELISA, IHC, WB
Reactivity
Hu
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee. ✓
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
Aryl hydrocarbon hydroxylase | Cytochrome P(3)450 | Cytochrome P450 1A2 | Cytochrome P450 4 | p450 form 4 | p3-450 | p450(PA) | CP12 | CYP1A2 | CYPIA2 | Cytochrome p450 ia2 | Cytochrome P450-P3 | Dioxin-inducible P3-450
Recommended Dilution: ELISA
1:500 - 1:1000
Recommended Dilution: IHC
1:100 - 1:500
Recommended Dilution: WB
1:100 - 1:500
UniProt Number
P05177
NCBI GenBank
NM_000761 | NP_000752.2
SwissProt
P05177

Target

Target
Human CYP1A2
Antigen Species
Human
Epitope
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, cytochrome P450 1A2 (CYP1A2) is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. CYP1A2 is most active in catalyzing 2-hydroxylation. Caffeine is metabolized primarily by CYP1A2 in the liver through an initial N3-demethylation. It also acts in the metabolism of aflatoxin B1 and acetaminophen. CYP1A2 participates in the bioactivation of carcinogenic aromatic and heterocyclic amines. It catalizes the N-hydroxylation of heterocyclic amines and the O-deethylation of phenacetin.
Gene Name
CYP1A2

Antibody

Host Species
Rabbit
Clonality
Polyclonal

Immunogen

Immunogen
Human recombinant CYP1A2
Immunogen Type
Recombinant Immunogen

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, pH 7.4, 0.09% Sodium Azide
Preservative
Yes
Purification Method
Protein A Affinity

Storage & Handling

Storage Conditions
Store at -20°C. Avoid freeze-thaw cycles.
Recommended Storage Buffer
PBS

Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.