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Polyclonal Rabbit anti-Human BRCA1 Antibody (WB)

The BRCA1 Antibody is used in Western blot to detect BRCA1 in MDA-MB-435 cell lysate.

Polyclonal Rabbit anti-Human BRCA1 Antibody (WB)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Enzyme-Linked Immunosorbent Assay, Western Blot
Reactivity:Human, Mouse, Rat
Format:Liquid
See all Human BRCA1 antibodies →
$402.00each
Catalog Number: LS-C413739-0.1

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Overview

Description
BRCA1 antibody LS-C413739 is an unconjugated rabbit polyclonal antibody to BRCA1 from human. It is reactive with human, mouse and rat. Validated for ELISA and WB.
Application
ELISA, WB
Reactivity
Hu, Ms, Rt
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
BRCA1 | BROVCA1 | BRCC1 | Breast cancer 1, early onset | PPP1R53 | PSCP | PNCA4 | RING finger protein 53 | RNF53 | BRCAI | Breast cancer 1 early onset | IRIS
Recommended Dilution: ELISA
1:500 - 1:1000
Recommended Dilution: WB
1:100 - 1:500
UniProt Number
P38398
SwissProt
P38398

Target

Target
Human BRCA1
Antigen Species
Human
Epitope
Breast cancer type 1 susceptibility protein (BRCA1) plays a central role in DNA repair by facilitating cellular response to DNA repair. BRCA1 is required for appropriate cell cycle arrests after ionizing irradiation in both the S-phase and the G2 phase of the cell cycle. BRCA1 is part of the BRCA1-associated genome surveillance complex (BASC), which contains BRCA1, MSH2, MSH6, MLH1, ATM, BLM, PMS2 and the RAD50-MRE11-NBS1 protein complex. Defects in BRCA1 are a cause of genetic susceptibility to breast and ovarian cancers.
Gene Name
BRCA1

Antibody

Host Species
Rabbit
Clonality
Polyclonal

Immunogen

Immunogen
KLH-conjugated synthetic peptide from the N-Terminus of human BRCA1.
Immunogen Type
Synthetic Peptide (Linear)

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, pH 7.4, 0.09% sodium azide, 12.5% glycerol.
Preservative
Yes
Purification Method
Protein G Affinity

Storage & Handling

Storage Conditions
Store at -20°C. Avoid freeze-thaw cycles.
Recommended Storage Buffer
PBS

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