Polyclonal Rabbit anti-Human SLC5A11 / SMIT2 Antibody (WB)
Catalog Number: LS-C748223
2 sizes / from $281.00
Antibody: Rabbit Polyclonal
Applications: Immunohistochemistry (general), Western Blot
Reactivity: Human, Mouse, Rat
Format: Liquid
Immun histochemical analysis of cIAP1 expression in formalin-fixed, paraffin-embedded human gliomas from a brain tissue microarray using Polyclonal Antibody to cIAP1 at 1:2000. A. Two tissue cores showing a gemistocytoma, grade II tumor (left) and an anaplastic glioma-glioblastoma, grade IV tumor (right). A1 and A2, higher magnifications of the gemistocytoma. A3, higher magnification of the anaplastic glioma-glioblastoma. Hematoxylin-Eosin counterstain. Higher cIAP1 expression is seen in the less malignant tumor (gemistocytoma) than the more malignant anaplastic (glioma-glioblastoma) tumor.
Polyclonal Rabbit anti-Human BIRC2 / cIAP1 Antibody (aa158-175, IHC, WB)
Primary AntibodyLSBio Guarantee
| Antibody: | Rabbit Polyclonal |
| Applications: | Immunohistochemistry (general), Immunohistochemistry, Frozen, Immunohistochemistry, Paraffin, Immunoprecipitation, Western Blot |
| Reactivity: | Human |
| Format: | Liquid |
$394.00each
Catalog Number: LS-C148257-50
Catalog Number: LS-C148257
For bulk orders or custom formulations:
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- Description
- CIAP1 antibody LS-C148257 is an unconjugated rabbit polyclonal antibody to human cIAP1 (BIRC2) (aa158-175). Validated for IHC, IP and WB.
- Application
- IHC, IHC-F, IHC-P, IP, WB
- Reactivity
- Hu
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Polyclonal Antibodies
- Alternative Names
- API1 | BIRC2 | C-IAP1 | CIAP1 | Hiap-2 | IAP homolog B | HIAP2 | IAP-2 | RNF48 | Apoptosis inhibitor 1 | IAP2 | MIHB | RING finger protein 48
- Recommended Dilution: IHC-P
- 1:1000 - 1:5000
- Recommended Dilution: IP
- 1:50 - 1:200
- Recommended Dilution: WB
- 1:1000 - 1:2000
- UniProt Number
- Q13490
- NCBI GenBank
- NM_001166 | NP_001157.1
- SwissProt
- Q13490
Target
- Target
- Human BIRC2 / cIAP1
- Antigen Species
- Human
- Epitope
- CIAP1 has 618 amino acids and migrates at ~70 kD on SDS-PAGE. Observed molecular weights may vary as genes generally produce, by alternative splicing, multiple transcripts all with introns, putatively encoding multiple different protein isoforms. Additionally, proteins may undergo post translational modifications including phosphorylation, glycosylation and cleavage which can result in differential molecular weights. Protein modifications can vary between cell and tissue type, and proteins can migrate as one or multiple bands depending on the isoform expressed as well as post-translational modifications.
- Gene Name
- BIRC2
Antibody
- Host Species
- Rabbit
- Clonality
- Polyclonal
Immunogen
- Immunogen
- A synthetic peptide corresponding to amino acids 158-175 (PNPLNSRAVEDISSSRTN) of human cIAP1, GenBank no. gi|2497238. Percent identity by BLAST analysis: Human, Chimpanzee (100%); Gorilla, Orangutan (94%); Gibbon, Monkey (89%); Marmoset, Pig (83%); Mouse, Rat (61%).
- Immunogen Type
- Synthetic Peptide (Linear)
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- Antiserum, 0.05% sodium azide
- Volume
- 50 Microliter
- Preservative
- Yes
- Purification Method
- Unpurified (Serum / Ascites / Supernatant)
Storage & Handling
- Storage Conditions
- Store at -20°C. Aliquot to avoid freeze/thaw cycles.
