LSBio
Polyclonal Rabbit anti-Human ANAPC11 / APC11 Antibody (aa76-84, IHC, WB)

Polyclonal Rabbit anti-Human ANAPC11 / APC11 Antibody (aa76-84, IHC, WB)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Enzyme-Linked Immunosorbent Assay, Immunohistochemistry (general), Immunoprecipitation, Western Blot
Reactivity:Human
Format:Liquid
See all Human ANAPC11 / APC11 antibodies →
$579.00each
Catalog Number: LS-C19022-100

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Overview

Description
APC11 antibody LS-C19022 is an unconjugated rabbit polyclonal antibody to human APC11 (ANAPC11) (aa76-84). Validated for ELISA, IHC, IP and WB. Cited in 2 publications.
Application
ELISA, IHC, IP, WB
Reactivity
Hu
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
Apc11p | ANAPC11 | APC11 | Cyclosome subunit 11 | HSPC214
Recommended Dilution: ELISA
1:2000 - 1:10000
Recommended Dilution: WB
1:500 - 1:1000
UniProt Number
Q9NYG5
SwissProt
Q9NYG5

Target

Target
Human ANAPC11 / APC11
Antigen Species
Human
Epitope
Reacts with human and mouse APC11. Cross reactivity may also occur with APC11 from other sources. Sufficient sequence differences exist to suggest that this antibody would not react with other RING box proteins such as ROC1 and ROC2.
Gene Name
ANAPC11

Antibody

Host Species
Rabbit
Clonality
Polyclonal

Immunogen

Immunogen
This antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 76-84 of Human APC11 (C-terminal) coupled to KLH.
Immunogen Type
Synthetic Peptide (Linear)

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
Antiserum, 0.01% Sodium Azide
Concentration
85 mg/mL
Volume
100 Microliter
Preservative
Yes
Purification Method
Other

Storage & Handling

Storage Conditions
Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid freeze-thaw cycles. Centrifuge product if not completely clear after standing at room temperature.

Association with cullin partners protects ROC proteins from proteasome-dependent degradation. Ohta T, Michel JJ, Xiong Y. Oncogene. 1999;18:6758-66.

PubMed: 10597284


Activation of UBC5 ubiquitin-conjugating enzyme by the RING finger of ROC1 and assembly of active ubiquitin ligases by all cullins. Furukawa M, Ohta T, Xiong Y. The Journal of biological chemistry. 2002;277:15758-65.

PubMed: 11861641

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