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Polyclonal Goat anti-Human CCR2 Antibody (aa17-39, IHC, WB)

Immunohistochemistry of paraffin-embeddedi human spleen stained with Goat anti-Human CD192 (N-Terminal)

Polyclonal Goat anti-Human CCR2 Antibody (aa17-39, IHC, WB)

Primary AntibodyLSBio Guarantee
Antibody:Goat Polyclonal
Applications:Enzyme-Linked Immunosorbent Assay, Immunohistochemistry, Paraffin, Western Blot
Reactivity:Human
Format:Liquid
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$436.00each
Catalog Number: LS-C187841-0.1

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Overview

Description
CCR2 antibody LS-C187841 is an unconjugated goat polyclonal antibody to human CCR2 (aa17-39). Validated for ELISA, IHC and WB.
Application
ELISA, IHC-P, WB
Reactivity
Hu
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
C-C chemokine receptor type 2 | CD192 | Cc chemokine receptor 2 | CCR-2 | CCR2A | C-C CKR-2 | CKR2 | CD192 antigen | CKR2A | CKR2B | Mcp1 receptor | MCP-1 receptor | MCP-1-R | C-c chemokine receptor 2 | CC-CKR-2 | Cc-ckr2 | CCR2 | CCR2B | CMKBR2 | Mcp1r
Recommended Dilution: ELISA
1:60000
Recommended Dilution: IHC-P
1:200
Recommended Dilution: WB
1:1000
UniProt Number
P41597
NCBI GenBank
NP_001116868.1
SwissProt
P41597

Target

Target
Human CCR2
Antigen Species
Human
Epitope
Recognizes an epitope within the N-terminal (NT) region of human CD192, otherwise known as CCR2 (C-C chemokine receptor type 2), a transmembrane glycoprotein and member of the G-protein coupled receptor 1 family, which acts as a receptor for the chemokines MCP-1 (monocyte chemoattractant protein 1), MCP-3 and MCP-4. Interaction between CD192 and MCP-1 initiates chemotactic responses, through an increase in intracellular calcium levels. CD192 acts as a co-receptor with CD4 for HIV1 infection, and variations in CD192 are associated with relative resistance to HIV1.
Gene Name
CCR2

Antibody

Host Species
Goat
Clonality
Polyclonal
Isotype
IgG

Immunogen

Immunogen
Synthetic peptide C-GEEVTTFFDYDYGAPCHKFDVKQ corresponding to amino acids 17-39 within the N-Terminus of human CD192. Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey (100%); Orangutan (96%).
Immunogen Type
Synthetic Peptide (Linear)

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, 0.1% Sodium Azide, 0.1% BSA
Concentration
1 mg/mL
Preservative
Yes
Purification Method
Affinity Purified

Storage & Handling

Storage Conditions
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
Recommended Storage Buffer
PBS

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