This image was taken for the unconjugated form of this product. Other forms have not been tested.
POLR2A / RNA polymerase II Antibody (phospho-Ser, clone 4H8)
Primary AntibodyLSBio Guarantee
| Antibody: | Mouse Monoclonal |
| Applications: | Enzyme-Linked Immunosorbent Assay, Immunofluorescence, Immunoprecipitation, Western Blot |
| Reactivity: | Fruit Fly, Fungus / Yeast / Mold, Hamster, Human, Mouse, Plant |
| Format: | Liquid |
$394.00each
Catalog Number: LS-C49196-0.1
Catalog Number: LS-C49196
For bulk orders or custom formulations:
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- Description
- RNA polymerase II antibody LS-C49196 is an unconjugated mouse monoclonal antibody to RNA polymerase II (POLR2A) (pSer) from human. It is reactive with human, mouse, drosophila and other species. Validated for ELISA, IF, IP and WB. Cited in 1 publication.
- Application
- ELISA, IF, IP, WB
- Reactivity
- Dros, Fung, Ham, Hu, Ms, Plnt
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Monoclonal Antibodies
- Alternative Names
- HRPB220 | HsRPB1 | POLR2 | RpIILS | RPOL2 | POLR2A | RNA Polymerase II | RPO2 | POLRA | RNA polymerase II subunit B1 | RPB1 | RPBh1
- UniProt Number
- P24928
- NCBI GenBank
- NM_000937 | NP_000928.1
- SwissProt
- P24928
Target
- Target
- Human POLR2A / RNA polymerase II
- Antigen Species
- Human
- Epitope
- This recognizes the C-terminal repeat of the largest subunit of RNA polymerase II. It recognizes both unphosphorylated and phosphorylated forms.
- Gene Name
- POLR2A
Antibody
- Host Species
- Mouse
- Clonality
- Monoclonal
- Clone
- 4H8
Immunogen
- Immunogen
- 10 repeats of synthetic peptide YSPTSPS using chemically synthesized phospho-ser 5 YSPTSpPS (Human).
- Immunogen Type
- Synthetic Peptide (Linear)
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS
- Concentration
- 1 mg/mL
- Volume
- 0.1 Milliliter
- Preservative
- No
- Purification Method
- Protein G Affinity
Storage & Handling
- Storage Conditions
- Short term: store at 4°C. Long term: store at -20°C. Avoid freeze-thaw cycles.
- Recommended Storage Buffer
- PBS
SUMO2 conjugation of PCNA facilitates chromatin remodeling to resolve transcription-replication conflicts. Min Li, Xiaohua Xu, Chou-Wei Chang, Li Zheng, Binghui Shen, Yilun Liu. Nature communications. 2018 Jul;9:2706. PubMed: 30006506 PMC: PMC6045570