LSBio
POLG2 Antibody

Western blot analysis of extracts of various cell lines.

POLG2 Antibody

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Immunofluorescence, Immunohistochemistry (general), Western Blot
Reactivity:Human, Mouse, Rat
Format:Liquid
See all Human POLG2 antibodies →
$281.00each
Catalog Number: LS-C334882-20

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Overview

Description
POLG2 antibody LS-C334882 is an unconjugated rabbit polyclonal antibody to POLG2 from human. It is reactive with human, mouse and rat. Validated for IF, IHC and WB. Cited in 2 publications.
Application
IF, IHC, WB
Reactivity
Hu, Ms, Rt
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
MTPOLB | PEOA4 | POLG-BETA | POLGB | HP55 | p55 | POLG2
Recommended Dilution: IF/ICC
1:10 - 1:100
Recommended Dilution: IHC
1:50 - 1:200
Recommended Dilution: WB
1:500 - 1:2000
UniProt Number
Q9UHN1
SwissProt
Q9UHN1

Target

Target
Human POLG2
Antigen Species
Human
Epitope
Human POLG2
Gene Name
POLG2

Antibody

Host Species
Rabbit
Clonality
Polyclonal
Isotype
IgG

Immunogen

Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 216-485 of human POLG2 (NP_009146.2). HPVFDTKQIRNGVKSIGEKTEASLVWFTPPRTSNQWLDFWLRHRLQWWRKFAMSPSNFSSSDCQDEEGRKGNKLYYNFPWGKELIETLWNLGDHELLHMYPGNVSKLHGRDGRKNVVPCVLSVNGDLDRGMLAYLYDSFQLTENSFTRKKNLHRKVLKLHPCLAPIKVALDVGRGPTLELRQVCQGLFNELLENGISVWPGYLETMQSSLEQLYSKYDEMSILFTVLVTETTLENGLIHLRSRDTTMKEMMHISKLKDFLIKYISSAKNV
Immunogen Type
Fusion Protein (e.g., GST, MBP tag)

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, pH 7.3, 0.02% Sodium Azide, 50% Glycerol
Volume
20 Microliter
Preservative
Yes
Purification Method
Affinity Purified

Storage & Handling

Storage Conditions
Store at -20°C. Avoid freeze-thaw cycles.
Recommended Storage Buffer
PBS

RNase H1 Regulates Mitochondrial Transcription and Translation via the Degradation of 7S RNA. Aurelio Reyes, Joanna Rusecka, Katarzyna Tonska, Massimo Zeviani. Frontiers in genetics. 2020 Jan;10:1393.

PubMed: 32082360 · PMC: PMC7006045


DNA polymerase gamma mutations that impair holoenzyme stability cause catalytic subunit depletion10<sup> Venetian Institute of Molecular Medicine, via Orus 2-35128 Padova, Italy. Pedro Silva-Pinheiro, Carlos Pardo-Hernández, Aurelio Reyes, Lisa Tilokani, Anup Mishra, Raffaele Cerutti, Shuaifeng Li, Dieu-Hien Rozsivalova, Sebastian Valenzuela, Sukru A Dogan, Bradley Peter, Patricio Fernández-Silva, Aleksandra Trifunovic, Julien Prudent, Michal Minczuk, Laurence Bindoff , Bertil Macao, Massimo Zeviani , Maria Falkenberg, Carlo Viscomi. Nucleic acids research. 2021 May;49:5230-5248.

PubMed: 33956154 · PMC: PMC8136776

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