Formalin-paraffin human Melanoma stained with gp100 Rabbit Recombinant Monoclonal Antibody (PMEL/1825R).
PMEL / SILV / gp100 Antibody (clone PMEL/1825R, Azide-free, Carrier-free)
Primary AntibodyLSBio Guarantee
| Antibody: | Rabbit Recombinant Monoclonal |
| Applications: | Immunohistochemistry, Paraffin |
| Reactivity: | Human |
| Format: | Liquid |
$586.00each
Catalog Number: LS-C751359-100
Catalog Number: LS-C751359
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- Description
- Gp100 antibody LS-C751359 is an unconjugated rabbit recombinant monoclonal antibody to human gp100 (PMEL / SILV). Validated for IHC.
- Application
- IHC-P
- Reactivity
- Hu
- Nonreactive Species
- Dog, Rat
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Recombinant Antibodies
- Alternative Names
- gp100 | Melanocyte protein PMEL | Me20m/me20s | p100 | PMEL17 | Premelanosome protein | SIL | Silver homolog (mouse) | Silver, mouse, homolog of | Silver locus protein homolog | ME20-M | Me20-m/me20-s | ME20M | Melanocyte protein mel 17 | Melanocyte protein Pmel 17 | PMEL | Silver (mouse homolog) like | D12S53E | ME20 | Melanosomal matrix protein17 | SILV
- Recommended Dilution: IHC-P
- 0.5 - 1 µg/ml
- UniProt Number
- P40967
- NCBI GenBank
- NM_006928 | NP_008859.1
- SwissProt
- P40967
Target
- Target
- Human PMEL / SILV / gp100
- Antigen Species
- Human
- Epitope
- By immunohistochemistry, it specifically recognizes a protein in melanocytes and melanomas. This MAb reacts with junctional and blue nevus cells and variably with fetal and neonatal melanocytes. Intradermal nevi, normal adult melanocytes, and non-melanocytic cells are negative. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin. Metastatic amelanotic melanoma can often be confused with a variety of poorly differentiated carcinomas, large cell lymphomas, and sarcomas using H & E stains alone. It is also difficult to differentiate melanoma from spindle cell carcinomas and various types of mesenchymal neoplasms. This MAb stains fetal and neonatal melanocytes, junctional and blue nevus cells, and malignant melanoma. This MAb also stains Angiomyolipoma (PEComa).
- Gene Name
- PMEL
Antibody
- Host Species
- Rabbit
- Clonality
- Recombinant Monoclonal
- Clone
- PMEL/1825R
- Isotype
- IgG
- Origin Species
- Human
Immunogen
- Immunogen
- Recombinant full-length human gp100 protein. Antigen Molecular Weight: 90-100 kDa
- Immunogen Type
- Recombinant Immunogen
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- 10 mM PBS
- Concentration
- 1 mg/mL
- Preservative
- No
- Purification Method
- Protein A/G Affinity
Storage & Handling
- Storage Conditions
- Store at -20°C to -80°C for up to 2 years.
- Recommended Storage Buffer
- 10 mM PBS