PIM3 / PIM-3 Antibody (FITC)

Primary AntibodyLSBio Guarantee

Antibody:	Rabbit Polyclonal
Applications:	Enzyme-Linked Immunosorbent Assay
Reactivity:	Human
Format:	Liquid

$300.00each

Catalog Number: LS-C501221-50

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Description: PIM-3 antibody LS-C501221 is an FITC-conjugated rabbit polyclonal antibody to human PIM-3 (PIM3). Validated for ELISA.
Application: ELISA
Reactivity: Hu
Intended Use: Research Use Only
Guarantees: This antibody carries the LSBio 100% Guarantee. ✓
Category: Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names: KID1 | Pim-3 oncogene | Serine/threonine kinase Pim-3 | Pim-3 | PIM3
UniProt Number: Q86V86
SwissProt: Q86V86

Target: Human PIM3 / PIM-3
Antigen Species: Human
Epitope: Proto-oncogene with serine/threonine kinase activity that can prevent apoptosis, promote cell survival and protein translation. May contribute to tumorigenesis through: the delivery of survival signaling through phosphorylation of BAD which induces release of the anti-apoptotic protein Bcl-X(L), the regulation of cell cycle progression, protein synthesis and by regulation of MYC transcriptional activity. Additionally to this role on tumorigenesis, can also negatively regulate insulin secretion by inhibiting the activation of MAPK1/3 (ERK1/2), through SOCS6. Involved also in the control of energy metabolism and regulation of AMPK activity in modulating MYC and PPARGC1A protein levels and cell growth.
Gene Name: PIM3

Immunogen: Recombinant Human Serine/threonine-protein kinase pim-3 protein (278-326AA)
Immunogen Type: Recombinant Immunogen

Storage Conditions: Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.
Recommended Storage Buffer: PBS

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