Immunohistochemical of paraffin-embedded H. liver section using PAH Antibody. Antibody was diluted at 1:25 dilution. A peroxidase-conjugated goat anti-rabbit IgG at 1:400 dilution was used as the secondary antibody, followed by DAB staining.
PH / PAH Antibody (aa127-161, clone 717CT21.1.1)
Primary AntibodyLSBio Guarantee
| Antibody: | Mouse Monoclonal |
| Applications: | Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot |
| Reactivity: | Human, Mouse, Rat |
| Format: | Liquid |
$401.00each
Catalog Number: LS-C344145-400
Catalog Number: LS-C344145
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- Description
- PAH antibody LS-C344145 is an unconjugated mouse monoclonal antibody to PAH (PH) (aa127-161) from human. It is reactive with human, mouse and rat. Validated for IHC and WB. Cited in 1 publication.
- Application
- IHC, IHC-P, WB
- Reactivity
- Hu, Ms, Rt
- Predicted Reactivity
- Bov
- Intended Use
- RUO
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Monoclonal Antibodies
- Alternative Names
- PAH | Phe-4-monooxygenase | PKU1 | PH | Phenylalanine 4-monooxygenase | Phe-4- monooxygenase | Phenylalanine hydroxylase | Phenylalanine-4-hydroxylase | PKU
- Recommended Dilution: WB
- 1:1000
- UniProt Number
- P00439
- NCBI GenBank
- NM_000277, NP_000268.1
- SwissProt
- P00439
Target
- Target
- Human PH / PAH
- Antigen Species
- Hu
- Epitope
- This PAH antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 127-161 amino acids from the Central region of human PAH.
- Gene Name
- PAH
Antibody
- Host Species
- Ms
- Clonality
- Monoclonal
- Clone
- 717CT21.1.1
- Isotype
- IgG1
- Light Chain
- κ
Immunogen
- Immunogen Type
- SP-Lin
Format
- Conjugate/Label
- Unconj
- Format
- Liquid
- Formulation
- PBS, 0.09% Sodium Azide
- Concentration
- 0.5 mg/mL
- Volume
- 400 Microliter
- Preservative
- Yes
- Purification Method
- Prot G
Storage & Handling
- Storage Conditions
- Maintain refrigerated at 2°C to 8°C for up to 6 months. For long term storage store at -20°C.
- Recommended Storage Buffer
- PBS
CRISPR/Cas9 generated knockout mice lacking phenylalanine hydroxylase protein as a novel preclinical model for human phenylketonuria10 Genomic Medicine Unit, Sanofi, 49 New York Avenue, Framingham, MA, 01701, USA. Sirkka.Kyostio-Moore@sanofi.com. Kuldeep Singh , Cathleen S Cornell, Robert Jackson, Mostafa Kabiri, Michael Phipps, Mitul Desai, Robert Fogle, Xiaoyou Ying, Gulbenk Anarat-Cappillino, Sarah Geller, Jennifer Johnson, Errin Roberts, Katie Malley, Tim Devlin, Matthew DeRiso, Patricia Berthelette, Yao V Zhang, Susan Ryan, Srinivas Rao, Beth L Thurberg, Dinesh S Bangari, Sirkka Kyostio-Moore. Scientific reports. 2021 Mar;11:7254. PubMed: 33790381 PMC: PMC8012645