PD-L2 / PDCD1LG2 / CD273 Antibody (clone TY25, FITC)
Primary AntibodyLSBio Guarantee
| Antibody: | Rat Monoclonal |
| Applications: | Flow Cytometry |
| Reactivity: | Mouse |
| Format: | Liquid |
$335.00each
Catalog Number: LS-C44894-0.1
Catalog Number: LS-C44894
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- Description
- CD273 antibody LS-C44894 is an FITC-conjugated rat monoclonal antibody to mouse CD273 (PD-L2 / PDCD1LG2). Validated for Flow.
- Application
- FC
- Reactivity
- Ms
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Monoclonal Antibodies
- Alternative Names
- B7 dendritic cell molecule | B7-DC | B7DC | BA574F11.2 | CD273 | Btdc | CD273 antigen | PD-L2 | PDCD1 ligand 2 | PD-1-ligand 2 | Programmed death ligand 2 | Butyrophilin B7-DC | PD-1 ligand 2 | PDCD1L2 | PDCD1LG2 | PDL2
- Recommended Dilution: FC
- 1:1 - 1:5
- UniProt Number
- Q9BQ51
- NCBI GenBank
- NM_025239 | NP_079515.2
- SwissProt
- Q9BQ51
Target
- Target
- Mouse PD-L2 / PDCD1LG2 / CD273
- Antigen Species
- Mouse
- Epitope
- Recognizes mouse CD273, a 42kD member of the B7 family, otherwise known as B7-dendritic cell (B7-DC), or programmed death ligand-2 (PD-L2). The expression of CD273 is restricted to a subpopulation of dendritic cells (DCs), and DCs and macrophages that have been stimulated with interferon gamma, GM-CSF or IL-4. CD273 has been identified as a ligand for PD-1(CD279), along with another B7 family member B7-H1 (CD279). Studies suggest that both CD273 and B7-H1 co-stimulate or inhibit T cell proliferation and cytokine production. Antibodies produced by clone TY25 are reported to block the binding of CD273 (B7-DC) to its receptor. XXX recommend the use of MCA2465EL for functional studies.
- Gene Name
- PDCD1LG2
Antibody
- Host Species
- Rat
- Clonality
- Monoclonal
- Clone
- TY25
- Isotype
- IgG2a
Immunogen
- Immunogen
- B7-DC transfected RAW264.7 cells
- Immunogen Type
- Cell-Based Immunization
Format
- Conjugate/Label
- Fluorescein Isothiocyanate
- Format
- Liquid
- Formulation
- PBS, 0.09% Sodium Azide, 1% BSA
- Concentration
- 0.1 mg/mL
- Preservative
- Yes
- Purification Method
- Protein G Affinity
Storage & Handling
- Storage Conditions
- Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Protect from light. Microcentrifugation recommended if solution contains precipitate.
- Recommended Storage Buffer
- PBS