Human Uterus: Formalin-Fixed, Paraffin-Embedded (FFPE)

PathPlus™ TLE1 / TLE 1 Antibody (aa 175-338, clone TLE1/2946R)

Primary AntibodyLSBio Guarantee

Antibody:	Rabbit Recombinant Monoclonal
Applications:	Immunohistochemistry (general)
Reactivity:	Human
Format:	Liquid

$536.00each

Catalog Number: LS-B16303-100

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Overview

Description: TLE 1 antibody LS-B16303 is an unconjugated rabbit recombinant monoclonal antibody to human TLE 1 (TLE1) (aa 175-338). Validated for IHC.
Application: IHC
Reactivity: Hu
Intended Use: Research Use Only
Guarantees: This product carries the LSBio 100% Guarantee. ✓
Category: Antibodies > Primary Antibodies > Recombinant Antibodies
Alternative Names: E(Sp1) homolog | ESG | GRG1 | TLE1 | Enhancer of split groucho 1 | ESG1
Recommended Dilution: IHC-P: 1:100
UniProt Number: Q04724
NCBI GenBank: NM_005077 | NP_005068.2
SwissProt: Q04724

Target

Target: TLE1 / TLE 1
Antigen Species: Human
Specificity: Key players in the Notch pathway are the TLE genes, which are human homologs of the Drosophila groucho gene. Groucho is a transcriptional repressor that plays a key role in neurogenesis, segmentation and sex determination. Transducin-like enhancer protein 1 (TLE1) is a protein that is encoded by the TLE1 gene and is involved in control of hematopoiesis, neuronal, and terminal epithelial differentiation. Positive immunohistochemical nuclear staining with anti-TLE-1 has been shown to be a useful addition to an IHC panel when differentiating synovial sarcoma from other soft tissue malignancies.
Epitope: Key players in the Notch pathway are the TLE genes, which are human homologs of the Drosophila groucho gene. Groucho is a transcriptional repressor that plays a key role in neurogenesis, segmentation and sex determination. Transducin-like enhancer protein 1 (TLE1) is a protein that is encoded by the TLE1 gene and is involved in control of hematopoiesis, neuronal, and terminal epithelial differentiation. Positive immunohistochemical nuclear staining with anti-TLE-1 has been shown to be a useful addition to an IHC panel when differentiating synovial sarcoma from other soft tissue malignancies.
Gene Name: TLE1