Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)

PathPlus™ THBD / CD141 / Thrombomodulin Antibody (aa 69-194, clone rTHBD/1591)

Primary AntibodyLSBio Guarantee

Antibody:	Mouse Recombinant Monoclonal
Applications:	Enzyme-Linked Immunosorbent Assay, Immunohistochemistry (general), Immunohistochemistry, Paraffin
Reactivity:	Human
Format:	Liquid

See all THBD / CD141 / Thrombomodulin antibodies â†’

$536.00each

Catalog Number: LS-B16258-100

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Overview

Description: Thrombomodulin antibody LS-B16258 is an unconjugated mouse recombinant monoclonal antibody to human Thrombomodulin (THBD / CD141) (aa 69-194). Validated for ELISA and IHC.
Application: ELISA, IHC, IHC-P
Reactivity: Hu
Intended Use: Research Use Only
Guarantees: This product carries the LSBio 100% Guarantee. ✓
Category: Antibodies > Primary Antibodies > Recombinant Antibodies
Alternative Names: BDCA3 | CD141 antigen | CD141 | AHUS6 | Fetomodulin | THBD | THPH12 | TM | THRM | Thrombomodulin
Recommended Dilution: ELISA: 2 - 4 µg/ml
Recommended Dilution: IHC-P: 1:50
UniProt Number: P07204
NCBI GenBank: NM_000361 | NP_000352.1
SwissProt: P07204

Target

Target: THBD / CD141 / Thrombomodulin
Antigen Species: Human
Specificity: It recognizes a protein of 75 kDa , identified as Thrombomodulin. Thrombomodulin is a transmembrane glycoprotein with natural anticoagulant properties. It is normally expressed by a restricted number of cells, such as endothelial and mesothelial cells. In addition, synovial lining and syncytio-trophoblasts of placenta also express thrombomodulin. This protein is present in almost all of benign vascular tumors and majority of malignant vascular tumors (Kaposi s sarcoma, angiosarcoma, and epithelioid hemangioendothelioma). Hence, anti-thrombomodulin serves as a sensitive marker for lymphatic endothelial cells and their tumors. Recently, thrombomodulin antibody has been used for mesothelial cells and malignant mesotheliomas.
Epitope: It recognizes a protein of 75 kDa , identified as Thrombomodulin. Thrombomodulin is a transmembrane glycoprotein with natural anticoagulant properties. It is normally expressed by a restricted number of cells, such as endothelial and mesothelial cells. In addition, synovial lining and syncytio-trophoblasts of placenta also express thrombomodulin. This protein is present in almost all of benign vascular tumors and majority of malignant vascular tumors (Kaposi s sarcoma, angiosarcoma, and epithelioid hemangioendothelioma). Hence, anti-thrombomodulin serves as a sensitive marker for lymphatic endothelial cells and their tumors. Recently, thrombomodulin antibody has been used for mesothelial cells and malignant mesotheliomas.
Gene Name: THBD

Antibody

Host Species: Mouse
Clonality: Recombinant Monoclonal
Clone: rTHBD/1591
Origin Species: Human

Immunogen

Immunogen: Recombinant fragment (around aa 69-194) of human Thrombomodulin (CD141) protein. Antigen Molecular Weight: ~100 kDa
Immunogen Type: Recombinant Protein Fragment