Formalin-fixed, paraffin-embedded human Breast Carcinoma stained with SM-MHC Recombinant Rabbit Monoclonal Antibody (MYH11/2303R).

PathPlus™ SMMHC / MYH11 Antibody (clone MYH11/2303R)

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Antibody:	Rabbit Recombinant Monoclonal
Applications:	Immunohistochemistry (general)
Reactivity:	Human
Format:	Liquid

$536.00each

Catalog Number: LS-B16305-100

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Description: MYH11 antibody LS-B16305 is an unconjugated rabbit recombinant monoclonal antibody to human MYH11 (SMMHC). Validated for IHC.
Application: IHC
Reactivity: Hu
Intended Use: Research Use Only
Guarantees: This product carries the LSBio 100% Guarantee. ✓
Category: Antibodies > Primary Antibodies > Recombinant Antibodies
Alternative Names: AAT4 | FAA4 | KIAA0866 | Myosin-11 | MYH11 | Myosin heavy chain 11 | SMHC | SMMHC
Recommended Dilution: IHC-P: 1:100
UniProt Number: P35749
NCBI GenBank: NM_002474 | NP_002465.1
SwissProt: P35749

Target: SMMHC / MYH11
Antigen Species: Human
Specificity: Smooth muscle myosin heavy chain (SM-MHC) is a cytoplasmic structural protein, which is a major component of the contractile apparatus in smooth muscle cells. Expression of smooth muscle myosin is developmentally regulated, appearing early in smooth muscle development, and is specific for smooth muscle development. Two isoforms of smooth muscle myosin heavy chain have been identified, designated MHC-1 and MHC-2. The antibody may be useful for the study of breast tumors as the presence of an intact layer of myoepithelial cells is an important feature, which may distinguish benign breast lesions and carcinoma in situ from invasive tumors.
Epitope: Smooth muscle myosin heavy chain (SM-MHC) is a cytoplasmic structural protein, which is a major component of the contractile apparatus in smooth muscle cells. Expression of smooth muscle myosin is developmentally regulated, appearing early in smooth muscle development, and is specific for smooth muscle development. Two isoforms of smooth muscle myosin heavy chain have been identified, designated MHC-1 and MHC-2. The antibody may be useful for the study of breast tumors as the presence of an intact layer of myoepithelial cells is an important feature, which may distinguish benign breast lesions and carcinoma in situ from invasive tumors.
Gene Name: MYH11

Immunogen: Recombinant full-length human MYH11 protein. Antigen Molecular Weight: 205 kDa (MHC-1) and 200 kDa (MHC-2)
Immunogen Type: Full-Length Recombinant Protein