SDC1 / Syndecan 1 / CD138 Antibody
Catalog Number: LS-C489358-100
100 µL / $309.00
Antibody: Rabbit Polyclonal
Applications: Enzyme-Linked Immunosorbent Assay
Reactivity: Human
Format: Liquid
Anti-SDC1 / Syndecan 1 / CD138 antibody IHC staining of human tonsil, squamous epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. This image was taken for the unconjugated form of this product. Other forms have not been tested.
PathPlus™ SDC1 / Syndecan 1 / CD138 Antibody (clone B-A38)
Primary AntibodyLSBio Guarantee
| Antibody: | Mouse Monoclonal |
| Applications: | Flow Cytometry, Immunofluorescence, Immunohistochemistry (general), Immunohistochemistry, Frozen, Immunohistochemistry, Paraffin, Western Blot |
| Reactivity: | Human |
| Format: | Liquid |
$470.00each
Catalog Number: LS-B9360-0.05
Catalog Number: LS-B9360
For bulk orders or custom formulations:
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- Description
- CD138 antibody LS-B9360 is an unconjugated mouse monoclonal antibody to human CD138 (SDC1 / Syndecan 1). Validated for Flow, IF, IHC and WB. Cited in 2 publications.
- Application
- FC, IF, IHC, IHC-F, IHC-P, WB
- Reactivity
- Hu
- Intended Use
- Research Use Only
- Guarantees
- This product carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Monoclonal Antibodies
- Alternative Names
- CD138 antigen | SDC1 | SDC | SYND1 | Syndecan | Syndecan 1 | Syndecan-1 | CD138 | Syndecan proteoglycan 1
- Recommended Dilution: FC
- 1:1
- Recommended Dilution: IHC-F
- 1:100 - 1:500
- Recommended Dilution: IHC-P
- 1:100 - 1:500
- UniProt Number
- P18827
- NCBI GenBank
- NM_002997 | NP_002988.3
- SwissProt
- P18827
Target
- Target
- SDC1 / Syndecan 1 / CD138
- Antigen Species
- Human
- Specificity
- Recognizes a heparan sulfate rich membrane glycoprotein of 200kD known as Syndecan-1 (CD138). Syndecan functions as a receptor for collagen, fibronectin and thrombospondin. Stains all plasma cells and plasma cell lines. No staining of other leucocytes is seen in peripheral blood or bone marrow, although some ALL cell lines express the antigen weakly. Some staining of epithelial and endothelial cells may be seen in immunohistology
- Epitope
- Recognizes a heparan sulfate rich membrane glycoprotein of 200kD known as Syndecan-1 (CD138). Syndecan functions as a receptor for collagen, fibronectin and thrombospondin. Stains all plasma cells and plasma cell lines. No staining of other leucocytes is seen in peripheral blood or bone marrow, although some ALL cell lines express the antigen weakly. Some staining of epithelial and endothelial cells may be seen in immunohistology.
- Gene Name
- SDC1
Antibody
- Host Species
- Mouse
- Clonality
- Monoclonal
- Clone
- B-A38
- Origin Species
- Human
Immunogen
- Immunogen
- U266 cell line
- Immunogen Type
- Cell-Based Immunization
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS, 0.09% Sodium Azide, 1% BSA
- Concentration
- 0.1 mg/mL
- Animal Free
- No
- Carrier-Free
- No
- Preservative
- Yes
- Purification Method
- Protein G Affinity
Storage & Handling
- Storage Conditions
- Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
- Recommended Storage Buffer
- PBS
Halting the vicious cycle within the multiple myeloma ecosystem: blocking JAM-A on bone marrow endothelial cells restores the angiogenic homeostasis and suppresses tumor progression. Antonio G Solimando, Matteo C Da Vià, Patrizia Leone, Paola Borrelli, Giorgio A Croci, Paula Tabares, Andreas Brandl, Giuseppe Di Lernia, Francesco P Bianchi, Silvio Tafuri, Torsten Steinbrunn, Alessandra Balduini, Assunta Melaccio, Simona De Summa, Antonella Argentiero, Hilka Rauert-Wunderlich, Maria A Frassanito, Paolo Ditonno, Erik Henke, Wolfram Klapper, Roberto Ria, Carolina Terragna, Leo Rasche, Andreas Rosenwald, Martin K Kortüm, Michele Cavo, Domenico Ribatti, Vito Racanelli, Hermann Ein. Haematologica. 2020 April.
PubMed: 32354870 · PMC: PMC8252928
Acetyl-CoA Synthetase 2: A Critical Linkage in Obesity-Induced Tumorigenesis in Myeloma. Zongwei Li, Huan Liu, Jin He, Zhiqiang Wang, Zheng Yin, Gichun You, Zhiming Wang, Richard E Davis, Pei Lin, P Leif Bergsagel, Elisabet E Manasanch, Stephen T C Wong, Nestor F Esnaola, Jenny C Chang, Robert Z Orlowski, Qing Yi, Jing Yang. The Breast : official journal of the European Society of Mastology. 2021 January;33:78-93e7.
PubMed: 33406405 · PMC: PMC7799390
