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PathPlus™ Recombinant Monoclonal Rabbit anti-Human S100B / S100 Beta Antibody (clone S100B/1706R, IHC)

Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE)

PathPlus™ Recombinant Monoclonal Rabbit anti-Human S100B / S100 Beta Antibody (clone S100B/1706R, IHC)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Recombinant Monoclonal
Applications:Immunohistochemistry (general)
Reactivity:Human
Format:Liquid
See all S100B / S100 Beta antibodies →
$536.00each
Catalog Number: LS-B16298-100

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Overview

Description
S100 Beta antibody LS-B16298 is an unconjugated rabbit recombinant monoclonal antibody to human S100 Beta (S100B). Validated for IHC.
Application
IHC
Reactivity
Hu
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee. ✓
Category
Antibodies > Primary Antibodies > Recombinant Antibodies
Alternative Names
NEF | S100B | Protein S100-B | S100 | S100 calcium binding protein B | S100 calcium-binding protein B | S100beta | S-100 protein beta chain | S-100 protein subunit beta | S100-B
Recommended Dilution: IHC-P
1:100
UniProt Number
P04271
NCBI GenBank
NM_006272 | NP_006263.1
SwissProt
P04271

Target

Target
S100B / S100 Beta
Antigen Species
Human
Specificity
S100 belongs to the family of calcium binding proteins. S100A and S100B proteins are two members of the S100 family. S100A is composed of an alpha and a beta chain whereas S100B is composed of two beta chains. This antibody is specific against an epitope located on the beta-chain (i.e. in S-100A and S-100B) but not on the alpha-chain of S-100 (i.e. in S-100A and S100A0). This antibody can be used to localize S-100A and S-100B in various tissue sections. S-100 protein has been found in normal melanocytes, Langerhans cells, histiocytes, chondrocytes, lipocytes, skeletal and cardiac muscle, Schwann cells, epithelial and myoepithelial cells of the breast, salivary and sweat glands, as well as in glial cells. Neoplasms derived from these cells also express S-100 protein, albeit non-uniformly. A large number of well-differentiated tumors of the salivary gland, adipose and cartilaginous tissue, and Schwann cell-derived tumors express S-100 protein. Almost all malignant melanomas and cases of histiocytosis X are positive for S-100 protein.
Epitope
S100 belongs to the family of calcium binding proteins. S100A and S100B proteins are two members of the S100 family. S100A is composed of an alpha and a beta chain whereas S100B is composed of two beta chains. This antibody is specific against an epitope located on the beta-chain (i.e. in S-100A and S-100B) but not on the alpha-chain of S-100 (i.e. in S-100A and S100A0). This antibody can be used to localize S-100A and S-100B in various tissue sections. S-100 protein has been found in normal melanocytes, Langerhans cells, histiocytes, chondrocytes, lipocytes, skeletal and cardiac muscle, Schwann cells, epithelial and myoepithelial cells of the breast, salivary and sweat glands, as well as in glial cells. Neoplasms derived from these cells also express S-100 protein, albeit non-uniformly. A large number of well-differentiated tumors of the salivary gland, adipose and cartilaginous tissue, and Schwann cell-derived tumors express S-100 protein. Almost all malignant melanomas and cases of histiocytosis X are positive for S-100 protein.
Gene Name
S100B

Antibody

Host Species
Rabbit
Clonality
Recombinant Monoclonal
Clone
S100B/1706R
Origin Species
Human

Immunogen

Immunogen
Recombinant full-length human S100B protein. Antigen Molecular Weight: 10-12 kDa
Immunogen Type
Full-Length Recombinant Protein

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
10 mM PBS, 0.05% BSA, 0.05% Sodium Azide
Concentration
200 µg/mL
Animal Free
No
Carrier-Free
No
Preservative
Yes
Purification Method
Protein A Affinity

Storage & Handling

Storage Conditions
Store at 2°C to 8°C for up to 2 years.
Recommended Storage Buffer
10 mM PBS

Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.