LSBio
PathPlus™ Recombinant Monoclonal Rabbit anti-Human PECAM-1 / CD31 Antibody (clone C31/1395R, IHC, WB)

Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)

PathPlus™ Recombinant Monoclonal Rabbit anti-Human PECAM-1 / CD31 Antibody (clone C31/1395R, IHC, WB)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Recombinant Monoclonal
Applications:Flow Cytometry, Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot
Reactivity:Human
Format:Liquid
See all PECAM-1 / CD31 antibodies →
$536.00each
Catalog Number: LS-B16292-100

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Overview

Description
CD31 antibody LS-B16292 is an unconjugated rabbit recombinant monoclonal antibody to human CD31 (PECAM-1). Validated for Flow, IHC and WB.
Application
FC, IHC, IHC-P, WB
Reactivity
Hu
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Recombinant Antibodies
Alternative Names
CD31 | CD31 antigen | EndoCAM | PECA1 | PECAM1 | PECAM-1 | GPIIA
Recommended Dilution: FC
1 - 2 µg/10E6 cells
Recommended Dilution: IHC-P
1:100
Recommended Dilution: WB
1 - 2 µg/ml
UniProt Number
P16284
SwissProt
P16284

Target

Target
PECAM-1 / CD31
Antigen Species
Human
Specificity
CD31 (PECAM-1) is a transmembrane glycoprotein member of the immunoglobulin supergene family of adhesion molecules. CD31 is expressed by stem cells of the hematopoietic system and is primarily used to identify and concentrate these cells for experimental studies as well as for bone marrow transplantation. Anti-CD31 has shown to be highly specific and sensitive for vascular endothelial cells. Staining of nonvascular tumors (excluding hematopoietic neoplasms) is rare. CD31 MAb reacts with normal, benign, and malignant endothelial cells which make up blood vessel lining. The level of CD31 expression can help to determine the degree of tumor angiogenesis, and a high level of CD31 expression may imply a rapidly growing tumor and potentially a predictor of tumor recurrence.
Epitope
CD31 (PECAM-1) is a transmembrane glycoprotein member of the immunoglobulin supergene family of adhesion molecules. CD31 is expressed by stem cells of the hematopoietic system and is primarily used to identify and concentrate these cells for experimental studies as well as for bone marrow transplantation. Anti-CD31 has shown to be highly specific and sensitive for vascular endothelial cells. Staining of nonvascular tumors (excluding hematopoietic neoplasms) is rare. CD31 MAb reacts with normal, benign, and malignant endothelial cells which make up blood vessel lining. The level of CD31 expression can help to determine the degree of tumor angiogenesis, and a high level of CD31 expression may imply a rapidly growing tumor and potentially a predictor of tumor recurrence.
Gene Name
PECAM1

Antibody

Host Species
Rabbit
Clonality
Recombinant Monoclonal
Clone
C31/1395R
Origin Species
Human

Immunogen

Immunogen
Recombinant full-length human CD31 protein. Antigen Molecular Weight: ~100 kDa (endothelium) and ~130 kDa (platelets)
Immunogen Type
Full-Length Recombinant Protein

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
10 mM PBS, 0.05% BSA, 0.05% Sodium Azide
Concentration
0.2 mg/mL
Animal Free
No
Carrier-Free
No
Preservative
Yes
Purification Method
Protein A/G Affinity

Storage & Handling

Storage Conditions
Store at 2°C to 8°C for up to 2 years.
Recommended Storage Buffer
10 mM PBS

Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.