LSBio
PathPlus™ Recombinant Monoclonal Rabbit anti-Human KLK3 / PSA Antibody (clone KLK3/2871R, IHC)

Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)

PathPlus™ Recombinant Monoclonal Rabbit anti-Human KLK3 / PSA Antibody (clone KLK3/2871R, IHC)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Recombinant Monoclonal
Applications:Immunohistochemistry (general)
Reactivity:Human
Format:Liquid
See all KLK3 / PSA antibodies →
$536.00each
Catalog Number: LS-B16229-100

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Overview

Description
PSA antibody LS-B16229 is an unconjugated rabbit recombinant monoclonal antibody to human PSA (KLK3). Validated for IHC.
Application
IHC
Reactivity
Hu
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Recombinant Antibodies
Alternative Names
APS | Gamma-seminoprotein | Kallikrein-3 | Kallikrein-related peptidase 3 | P-30 antigen | KLK3 | Prostate specific antigen | Prostate-specific antigen | PSA | Semenogelase | KLK2A1 | Seminin
Recommended Dilution: IHC-P
1:100
UniProt Number
P07288
SwissProt
P07288

Target

Target
KLK3 / PSA
Antigen Species
Human
Specificity
Recognizes a single protein of 33-34 kDa , identified as the prostate specific antigen (PSA). This MAb is highly specific to PSA and stains prostatic secretory and ductal epithelium in both normal and neoplastic tissues. PSA is a chymotrypsin-like serine protease (kallikrein family) exclusively produced by the prostate epithelium, and abundant in seminal fluid. PSA can be detected in the sera of patients with prostatic carcinoma. It is predominantly complexed to a liver-derived serine protease inhibitor, alpha-1-antichymotrypsin (ACT). A higher proportion of serum PSA is complexed to ACT in prostate cancer than in benign prostate hyperplasia. This MAb makes an excellent pair with MAb A67-B/E3 for PSA tests.
Epitope
Recognizes a single protein of 33-34 kDa , identified as the prostate specific antigen (PSA). This MAb is highly specific to PSA and stains prostatic secretory and ductal epithelium in both normal and neoplastic tissues. PSA is a chymotrypsin-like serine protease (kallikrein family) exclusively produced by the prostate epithelium, and abundant in seminal fluid. PSA can be detected in the sera of patients with prostatic carcinoma. It is predominantly complexed to a liver-derived serine protease inhibitor, alpha-1-antichymotrypsin (ACT). A higher proportion of serum PSA is complexed to ACT in prostate cancer than in benign prostate hyperplasia. This MAb makes an excellent pair with MAb A67-B/E3 for PSA tests.
Gene Name
KLK3

Antibody

Host Species
Rabbit
Clonality
Recombinant Monoclonal
Clone
KLK3/2871R
Origin Species
Human

Immunogen

Immunogen
Recombinant full-length human KLK3 protein. Antigen Molecular Weight: 33-34 kDa
Immunogen Type
Full-Length Recombinant Protein

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
10 mM PBS, 0.05% BSA, 0.05% Sodium Azide
Concentration
200 µg/mL
Animal Free
No
Carrier-Free
No
Preservative
Yes
Purification Method
Protein A/G Affinity

Storage & Handling

Storage Conditions
Store at 2°C to 8°C for up to 2 years.
Recommended Storage Buffer
10 mM PBS

Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.