Human Parathyroid: Formalin-Fixed, Paraffin-Embedded (FFPE)

PathPlus™ PTH / Parathyroid Hormone Antibody (clone PTH/2295R)

Primary AntibodyLSBio Guarantee

Antibody:	Rabbit Recombinant Monoclonal
Applications:	Immunohistochemistry (general)
Reactivity:	Human
Format:	Liquid

See all PTH / Parathyroid Hormone antibodies â†’

$536.00each

Catalog Number: LS-B16293-100

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Overview

Description: Parathyroid Hormone antibody LS-B16293 is an unconjugated rabbit recombinant monoclonal antibody to human Parathyroid Hormone (PTH). Validated for IHC.
Application: IHC
Reactivity: Hu
Intended Use: Research Use Only
Guarantees: This product carries the LSBio 100% Guarantee. ✓
Category: Antibodies > Primary Antibodies > Recombinant Antibodies
Alternative Names: Parathyroid hormone | Parathyroid hormone 1 | PTH | Parathyrin | Parathormone | PTH1
Recommended Dilution: IHC-P: 1:100
UniProt Number: P01270
NCBI GenBank: NM_000315 | NP_000306.1
SwissProt: P01270

Target

Target: PTH / Parathyroid Hormone
Antigen Species: Human
Specificity: Epitope of this MAb maps in between aa 1-34. PTH is a hormone produced by the parathyroid gland that regulates the concentration of calcium and phosphorus in extracellular fluid. This hormone elevates blood Ca2+ levels by dissolving the salts in bone and preventing their renal excretion. It is produced in the parathyroid gland as an 84 amino acid single chain polypeptide. It can also be secreted as N-terminal truncated fragments or C-terminal fragments after intracellular degradation, as in case of hypercalcemia. Defects in this gene are a cause of familial isolated hypoparathyroidism (FIH) - also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism.
Epitope: Epitope of this MAb maps in between aa 1-34. PTH is a hormone produced by the parathyroid gland that regulates the concentration of calcium and phosphorus in extracellular fluid. This hormone elevates blood Ca2+ levels by dissolving the salts in bone and preventing their renal excretion. It is produced in the parathyroid gland as an 84 amino acid single chain polypeptide. It can also be secreted as N-terminal truncated fragments or C-terminal fragments after intracellular degradation, as in case of hypercalcemia. Defects in this gene are a cause of familial isolated hypoparathyroidism (FIH) - also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism.
Gene Name: PTH

Antibody

Host Species: Rabbit
Clonality: Recombinant Monoclonal
Clone: PTH/2295R
Origin Species: Human

Immunogen

Immunogen: Synthetic peptide corresponding to amino acids 1 to 34 of mature PTH conjugated to a carrier. Antigen Molecular Weight: 9 kDa
Immunogen Type: Synthetic Peptide (Linear)