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PathPlus™ Polyclonal Rabbit anti-Mouse MRE11A / MRE11 Antibody (IHC, WB)

Human Breast: Formalin-Fixed, Paraffin-Embedded (FFPE)

PathPlus™ Polyclonal Rabbit anti-Mouse MRE11A / MRE11 Antibody (IHC, WB)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Enzyme-Linked Immunosorbent Assay, Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot
Reactivity:Mouse
Format:Liquid
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$526.00each
Catalog Number: LS-B1447-50

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Overview

Description
MRE11 antibody LS-B1447 is an unconjugated rabbit polyclonal antibody to mouse MRE11 (MRE11A). Validated for ELISA, IHC and WB. Cited in 1 publication.
Application
ELISA, IHC, IHC-P, WB
Reactivity
Ms
Predicted Reactivity
Rat
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
AT-like disease | Endo/exonuclease Mre11 | HNGS1 | MRE11 | MRE11 homolog 1 | MRE11 homolog A | MRE11B | ATLD | MRE11A
Recommended Dilution: ELISA
1:10000 - 1:50000
Recommended Dilution: IHC-P
2.5 µg/ml
Recommended Dilution: WB
1:500 - 1:2000
UniProt Number
P49959
SwissProt
P49959

Target

Target
MRE11A / MRE11
Antigen Species
Mouse
Specificity
A BLAST analysis was used to suggest cross reactivity with Mre11 protein from rat (94% homology). Based on protein sequence homology also expect partial reactivity against Mre11 homologues from macaque (88%), human (84%) and dog (82%). This sequence shows less than 75% homology to homologues from bovine, Xenopus, chicken, chimpanzee and zebrafish sources. Reactivity against homologues from other sources is not known.
Epitope
A BLAST analysis was used to suggest cross reactivity with Mre11 protein from rat (94% homology). Based on protein sequence homology also expect partial reactivity against Mre11 homologues from macaque (88%), human (84%) and dog (82%). This sequence shows less than 75% homology to homologues from bovine, Xenopus, chicken, chimpanzee and zebrafish sources. Reactivity against homologues from other sources is not known.
Gene Name
MRE11

Antibody

Host Species
Rabbit
Clonality
Polyclonal
Origin Species
Human

Immunogen

Immunogen
This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a recombinant protein corresponding to amino acids 68-706 of mouse Mre11 protein.

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
0.02 M Potassium Phosphate, pH 7.2, 0.15 M NaCl, 0.01% Sodium Azide
Concentration
1 mg/mL
Animal Free
No
Carrier-Free
Yes
Preservative
Yes
Purification Method
Affinity Purified

Storage & Handling

Storage Conditions
Store at 4°C or -20°C. Avoid freeze-thaw cycles.
Recommended Storage Buffer
0.02 M Potassium Phosphate, 0.15 M NaCl
Virion assembly factories in the nucleus of polyomavirus-infected cells. Erickson KD, Bouchet-Marquis C, Heiser K, Szomolanyi-Tsuda E, Mishra R, Lamothe B, Hoenger A, Garcea RL. PLoS pathogens. 2012;8:e1002630. PubMed: 22496654 PMC: PMC3320610

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