LSBio
PathPlus™ Polyclonal Rabbit anti-Human LPAR3 / LPA3 / EDG7 Antibody (Cytoplasmic Domain, IHC)

Anti-LPAR3 / LPA3 / EDG7 antibody IHC of human Breast, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

PathPlus™ Polyclonal Rabbit anti-Human LPAR3 / LPA3 / EDG7 Antibody (Cytoplasmic Domain, IHC)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Immunohistochemistry (general), Immunohistochemistry, Paraffin
Reactivity:Bovine, Dog, Hamster, Horse, Human, Mammal (Other), Mouse, Non-Human Primate, Rat
Format:Liquid
See all LPAR3 / LPA3 / EDG7 antibodies →
$470.00each
Catalog Number: LS-A1014-50

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Overview

Description
EDG7 antibody LS-A1014 is an unconjugated rabbit polyclonal antibody to EDG7 (LPAR3 / LPA3) (Cytoplasmic Domain) from human. It is reactive with human, mouse, rat and other species. Validated for IHC. Tested on 20 paraffin-embedded human tissues. Cited in 2 publications.
Application
IHC, IHC-P
Reactivity
Bov, Can, Ham, Hr, Hu, Mml, Ms, NHP, Rt
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
EDG7 | Edg-7 | LPA receptor 3 | LPAR3 | HOFNH30 | LPA3 | RP4-678I3 | LP-A3 | LPA receptor EDG7 | LPA-3 | Edg7/LPA3
Recommended Dilution: IHC-P
10 µg/ml
UniProt Number
Q9UBY5
SwissProt
Q9UBY5

Target

Target
LPAR3 / LPA3 / EDG7
Antigen Species
Human
Specificity
Human EDG7. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Epitope
Human EDG7. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Gene Name
LPAR3

Antibody

Host Species
Rabbit
Clonality
Polyclonal

Immunogen

Immunogen
Synthetic 16 amino acid peptide from 3rd cytoplasmic domain of human EDG7. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Bovine, Dog, Bat, Hamster, Elephant, Horse, Opossum, Platypus (100%); Panda (94%); Pig, Turkey, Chicken (88%); Xenopus (81%).
Immunogen Type
Synthetic Peptide (Linear)

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, 0.1% Sodium Azide
Concentration
1 mg/mL
Animal Free
No
Carrier-Free
Yes
Preservative
Yes
Purification Method
Affinity Purified

Storage & Handling

Storage Conditions
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Recommended Storage Buffer
PBS

Reduced expression of biomarkers associated with the implantation window in women with endometriosis. Qingxiang Wei, J. Benjamin St. Clair, Teresa Fu, Pamela Stratton, Lynnette K. Nieman. Fertility and sterility. 2009;91:1686-91.

PubMed: 18672236 · PMC: PMC2697117


Elevated plasma levels of lysophosphatidic acid and aberrant expression of lysophosphatidic acid receptors in adenomyosis. Yang B, Wang L, Wan X, Li Y, Yu X, Qin Y, Luo Y, Wang F, Huang O. BMC women's health. 2017 November;17:118.

PubMed: 29178922 · PMC: PMC5702234


Lysophosphatidic acid acts on LPA1 receptor to increase H2O2 during flow-induced dilation in human adipose arterioles. Dawid S Chabowski, Andrew O Kadlec. Karima Ait-Aissa, Joseph C Hockenberry, Paul J Pearson, Andreas M Beyer, David D Gutterman. #N/A. 2018 August;175:4266-4280.

PubMed: 30153326 · PMC: PMC6193883

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