Polyclonal Chicken GFP Antibody (clone IQGFP6 Polyclonal, WB)
Catalog Number: LS-C827997-50
50 µL (1 mg/mL) / $492.00
Antibody: Chicken Polyclonal
Applications: Enzyme-Linked Immunosorbent Assay, Western Blot
Format: Liquid
Anti-HTR4 / 5-HT4 Receptor antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
PathPlus™ Polyclonal Rabbit anti-Human HTR4 / 5-HT4 Receptor Antibody (Cytoplasmic Domain, IHC)
Primary AntibodyLSBio Guarantee
| Antibody: | Rabbit Polyclonal |
| Applications: | Immunohistochemistry (general), Immunohistochemistry, Paraffin |
| Reactivity: | Bovine, Dog, Horse, Human, Mammal (Other), Non-Human Primate, Pig, Rabbit |
| Format: | Liquid |
$449.00each
Catalog Number: LS-A2685-50
Catalog Number: LS-A2685
For bulk orders or custom formulations:
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- Description
- 5-HT4 Receptor antibody LS-A2685 is an unconjugated rabbit polyclonal antibody to 5-HT4 Receptor (HTR4) (Cytoplasmic Domain) from human. It is reactive with human, bat, bovine and other species. Validated for IHC. Cited in 2 publications.
- Application
- IHC, IHC-P
- Reactivity
- Bov, Can, Hr, Hu, Mml, NHP, Por, Rb
- Predicted Reactivity
- Hamster, Mouse, Rat
- Intended Use
- Research Use Only
- Guarantees
- This product carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Polyclonal Antibodies
- Alternative Names
- 5-ht4 | 5-HT4 | 5-HT4R | 5-HT-4 | 5HT4 receptor | 5-HT4 receptor | 5-hydroxytryptamine 4 receptor | 5-hydroxytryptamine receptor 4 | Serotonin 5-HT-4a receptor | Serotonin receptor 4 | Cardiac 5-HT4 receptor | HTR4 | Serotonin 4 receptor | Serotonin 5-HT-4 receptor
- UniProt Number
- Q13639
- NCBI GenBank
- NM_000870 | NP_000861.1
- SwissProt
- Q13639
Recommended Dilution
| Application | Dilution |
|---|---|
| IHC-P | 15 - 20 µg/ml |
Target
- Target
- HTR4 / 5-HT4 Receptor
- Antigen Species
- Human
- Specificity
- Human 5HT4 Receptor. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
- Epitope
- Human 5HT4 Receptor. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
- Gene Name
- HTR4
Antibody
- Host Species
- Rabbit
- Clonality
- Polyclonal
Immunogen
- Immunogen
- Synthetic 15 amino acid peptide from 3rd cytoplasmic domain of human 5HT4 Receptor. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Elephant, Panda, Dog, Bat, Bovine, Rabbit, Horse, Pig (100%); Mouse, Rat, Hamster (93%); Guinea pig, Platypus (87%); Lizard (80%).
- Immunogen Type
- Synthetic Peptide (Linear)
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS, 0.1% Sodium Azide
- Concentration
- 1 mg/mL
- Animal Free
- No
- Carrier-Free
- Yes
- Preservative
- Yes
- Purification Method
- Affinity Purified
Storage & Handling
- Storage Conditions
- Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
- Recommended Storage Buffer
- PBS
Role of cAMP/PKA pathway and T-type calcium channels in the mechanism of action of serotonin in human adrenocortical cells. Louiset E, Duparc C, Lenglet S, Gomez-Sanchez CE, Lefebvre H. Molecular and cellular endocrinology. 2017 February;441:99-107.
PubMed: 27743992 · PMC: PMC5465225
Illicit Upregulation of Serotonin Signaling Pathway in Adrenals of Patients With High Plasma or Intra-Adrenal ACTH Levels. Le Mestre J, Duparc C, Reznik Y, Bonnet-Serrano F, Touraine P, Chabre O, Young J, Suzuki M, Sibony M, Gobet F, Stratakis CA, Raverot G, Bertherat J, Lefebvre H, Louiset E. The Journal of clinical endocrinology and metabolism. 2019 November;104:4967-4980.
PubMed: 31074783 · PMC: PMC6937520
