Monoclonal Mouse Biotin Antibody
Catalog Number: LS-C127042-200
200 µg / $755.00
Antibody: Mouse Monoclonal
Applications: Enzyme-Linked Immunosorbent Assay
Format: Liquid
Anti-B2M antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
PathPlus™ Monoclonal Mouse anti-Human B2M / Beta 2 Microglobulin Antibody (clone 2M2, IHC, WB)
Primary AntibodyLSBio Guarantee
| Antibody: | Mouse Monoclonal |
| Applications: | Enzyme-Linked Immunosorbent Assay, Flow Cytometry, Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot |
| Reactivity: | Human |
| Format: | Liquid |
$470.00each
Catalog Number: LS-B2200-100
Catalog Number: LS-B2200
For bulk orders or custom formulations:
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- Description
- Beta 2 Microglobulin antibody LS-B2200 is an unconjugated mouse monoclonal antibody to human Beta 2 Microglobulin (B2M). Validated for ELISA, Flow, IHC and WB. Cited in 6 publications.
- Application
- ELISA, FC, IHC, IHC-P, WB
- Reactivity
- Hu
- Intended Use
- Research Use Only
- Guarantees
- This product carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Monoclonal Antibodies
- Alternative Names
- B2M | Beta 2 Microglobulin | Beta-2-microglobulin | Beta-2-microglobin
- Recommended Dilution: IHC-P
- 5 µg/ml
- UniProt Number
- P61769
- NCBI GenBank
- NM_004048 | NP_004039.1
- SwissProt
- P61769
Target
- Target
- B2M / Beta 2 Microglobulin
- Antigen Species
- Human
- Specificity
- Purified human beta-2-microglobulin.
- Epitope
- Purified human beta-2-microglobulin.
- Gene Name
- B2M
Antibody
- Host Species
- Mouse
- Clonality
- Monoclonal
- Clone
- 2M2
- Origin Species
- Human
Immunogen
- Immunogen
- Purified human B2M / Beta-2-Microglobulin.
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS pH 7.2, 0.09% sodium azide.
- Concentration
- 0.5 mg/mL
- Animal Free
- No
- Carrier-Free
- Yes
- Preservative
- Yes
- Purification Method
- Affinity Purified
Storage & Handling
- Storage Conditions
- Store at 2°C to 8°C.
- Recommended Storage Buffer
- PBS
Distinct functions for the glycans of tapasin and heavy chains in the assembly of MHC class I molecules. Rizvi SM, Del Cid N, Lybarger L, Raghavan M. Journal of immunology (Baltimore, Md. : 1950). 2011;186:2309-20.
PubMed: 21263072 · PMC: PMC3057457
NLRC5 cooperates with the RFX transcription factor complex to induce MHC class I gene expression. Meissner TB, Liu YJ, Lee KH, Li A, Biswas A, van Eggermond MC, van den Elsen PJ, Kobayashi KS. Journal of immunology (Baltimore, Md. : 1950). 2012;188:4951-8.
PubMed: 22490869 · PMC: PMC3345046
Mutational dynamics and immune evasion in diffuse large B-cell lymphoma explored in a relapse-enriched patient series. Jillian F Wise, Sigve Nakken, Chloé B Steen, Daniel Vodák, Gunhild Trøen, Bjarne Johannessen, Ole Christian Lingjærde, Vera Hilden, Yngvild Nuvin Blaker, Baoyan Bai, Lars Birger Aasheim, Annika Pasanen, Susanne Lorenz, Anita Sveen, Ragnhild A Lothe, Ola Myklebost, Sirpa Leppä, Leonardo A Meza-Zepeda, Klaus Beiske, Michael S Lawrence, Eivind Hovig, June Helen Myklebust, Erlend B Smeland, Harald Holte. Blood Advances. 2020 May;4:1859-1866.
PubMed: 32374878 · PMC: PMC7218413
Targeted clearance of senescent cells using an antibody-drug conjugate against a specific membrane marker10<sup> The Ernest and Helen Scott Haematological Research Institute, University of Leicester, Leicester, UK. sm460@le.ac.uk. Marta Poblocka, Akang Leonard Bassey , Victoria M Smith, Marta Falcicchio , Ana Sousa Manso, Mohammad Althubiti , XiaoBo Sheng, Andrew Kyle, Ruth Barber, Mark Frigerio, Salvador Macip. Scientific reports. 2021 Oct;11:20358.
PubMed: 34645909 · PMC: PMC8514501
ß2<sub>-microglobulin triggers NLRP3 inflammasome activation in tumor-associated macrophages to promote multiple myeloma progression. Daniel Hofbauer, Dimitrios Mougiakakos, Luca Broggini, Mario Zaiss, Maike Büttner-Herold, Christian Bach, Bernd Spriewald, Frank Neumann, Savita Bisht, Jens Nolting, Robert Zeiser, Shaima'a Hamarsheh, Martin Eberhardt, Julio Vera, Cristina Visentin, Chiara Maria Giulia De Luca, Fabio Moda, Stefan Haskamp, Cindy Flamann, Martin Böttcher, Katrin Bitterer, Simon Völkl, Andreas Mackensen, Stefano Ricagno, Heiko Bruns. Immunity. 2021 August;54:1772-1787e9.
PubMed: 34289378