Formalin-fixed, paraffin-embedded Human Melanoma stained with MART-1 Rabbit Recombinant Monoclonal Antibody (MLANA/1761R) (AP-Fast Red).

PathPlus™ MLANA / Melan-A Antibody (clone MLANA/1761R)

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Antibody:	Rabbit Recombinant Monoclonal
Applications:	Immunohistochemistry (general)
Reactivity:	Human
Format:	Liquid

$536.00each

Catalog Number: LS-B16279-100

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Description: Melan-A antibody LS-B16279 is an unconjugated rabbit recombinant monoclonal antibody to human Melan-A (MLANA). Validated for IHC.
Application: IHC
Reactivity: Hu
Intended Use: Research Use Only
Guarantees: This product carries the LSBio 100% Guarantee. ✓
Category: Antibodies > Primary Antibodies > Recombinant Antibodies
Alternative Names: Antigen LB39-AA | Antigen SK29-AA | Melan-A | MLANA | Protein Melan-A | MART-1 | MART1 | Melan A
Recommended Dilution: IHC-P: 1:100
UniProt Number: Q16655
NCBI GenBank: NM_005511 | NP_005502.1
SwissProt: Q16655

Target: MLANA / Melan-A
Antigen Species: Human
Specificity: This antibody recognizes a protein doublet of 20-22 kDa , identified as MART-1 (Melanoma Antigen Recognized by T cells 1) or Melan-A. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Seven other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1, and GAGE-1. Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum. This MAb labels melanomas and other tumors showing melanocytic differentiation. It is also a useful positive-marker for angiomyolipomas. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin.
Epitope: This antibody recognizes MART-1 (Melanoma Antigen Recognized by T cells 1, Melan-A), a melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. MART-1 is present in melanosomes and endoplasmic reticulum. This antibody labels melanomas and other tumors showing melanocytic differentiation. It is also a useful positive-marker for angiomyolipomas. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin.
Gene Name: MLANA

Immunogen: Recombinant full-length hMART-1 protein. Antigen Molecular Weight: 20-22 kDa (doublet)
Immunogen Type: Full-Length Recombinant Protein