LSBio
PathPlus™ MAP2 Antibody (C-Terminus)

Anti-MAP2 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

PathPlus™ MAP2 Antibody (C-Terminus)

Primary AntibodyLSBio Guarantee
Antibody:Chicken Polyclonal
Applications:Immunohistochemistry (general), Immunohistochemistry, Paraffin
Reactivity:Bovine, Human, Mouse, Rat
Format:Liquid
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$383.00each
Catalog Number: LS-B290-0.05

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Overview

Description
MAP2 antibody LS-B290 is an unconjugated chicken polyclonal antibody to MAP2 (C-Terminus) from human. It is reactive with human, mouse, rat and other species. Validated for IHC. Cited in 8 publications.
Application
IHC, IHC-P
Reactivity
Bov, Hu, Ms, Rt
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
MAP2C | MAP-2 | MAP2 | MAP2A | MAP2B
Recommended Dilution: IHC-P
5 µg/ml
UniProt Number
P11137
SwissProt
P11137

Target

Target
MAP2
Antigen Species
Human
Specificity
C-terminus of human, mouse, rat, bovine MAP2, a neuronal dendrite marker
Gene Name
MAP2

Antibody

Host Species
Chicken
Clonality
Polyclonal
Origin Species
Human

Immunogen

Immunogen
Synthetic peptide from C-Terminus of human MAP2
Immunogen Type
Synthetic Peptide (Linear)

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, 0.02% Sodium Azide
Volume
0.05 Milliliter
Animal Free
No
Carrier-Free
Yes
Preservative
Yes
Purification Method
Ammonium Sulfate Precipitation

Storage & Handling

Storage Conditions
Short term: store at 4°C. Long term: store at -20°C. Avoid freeze-thaw cycles.
Recommended Storage Buffer
PBS

Activity-dependent dendritic spine shrinkage and growth involve downregulation of cofilin via distinct mechanisms. Calabrese B, Saffin JM, Halpain S. PloS one. 2014;9:e94787.

PubMed: 24740405 · PMC: PMC3989342


Frequent infection of cortical neurons by JC virus in patients with progressive multifocal leukoencephalopathy. Wüthrich C, Koralnik IJ. Journal of neuropathology and experimental neurology. 2012;71:54-65.

PubMed: 22157619 · PMC: PMC3246306


JC virus encephalopathy is associated with a novel agnoprotein-deletion JCV variant. Dang X, Wüthrich C, Gordon J, Sawa H, Koralnik IJ. PloS one. 2012;7:e35793.

PubMed: 22536439


Natalizumab-associated progressive multifocal leukoencephalopathy in a patient with multiple sclerosis: a postmortem study. Wüthrich C, Popescu BF, Gheuens S, Marvi M, Ziman R, Denq SP, Tham M, Norton E, Parisi JE, Dang X, Lucchinetti CF, Koralnik IJ. Journal of neuropathology and experimental neurology. 2013 November;72:1043-51.

PubMed: 24128680 · PMC: PMC4465443


Lack of Major Histocompatibility Complex Class I Upregulation and Restrictive Infection by JC Virus Hamper Detection of Neurons by T Lymphocytes in the Central Nervous System. Christian Wüthrich, Stephanie Batson, Igor J Koralnik. Journal of neuropathology and experimental neurology. 2015 August;74:791-803.

PubMed: 26115192 · PMC: PMC4506730


Demonstration of prion-like properties of mutant huntingtin fibrils in both in vitro and in vivo paradigms. Maria Masnata, Giacomo Sciacca, Alexander Maxan, Luc Bousset, Hélèna L Denis, Florian Lauruol, Linda David, Martine Saint-Pierre, Jeffrey H Kordower, Ronald Melki, Melanie Alpaugh, Francesca Cicchetti. Acta neuropathologica. 2019 June;137:981-1001.

PubMed: 30788585 · PMC: PMC6531424


JC Virus Infects Neurons and Glial Cells in the Hippocampus. Christian Wüthrich, Stephanie Batson, Matthew P Anderson, Lon R White, Igor J Koralnik. Journal of neuropathology and experimental neurology. 2016 Aug;75:712-717.

PubMed: 27297673 · PMC: PMC5909865


INF2-mediated actin filament reorganization confers intrinsic resilience to neuronal ischemic injury. Barbara Calabrese, Steven L Jones, Yoko Shiraishi-Yamaguchi, Michael Lingelbach, Uri Manor, Tatyana M Svitkina, Henry N Higgs, Andy Y Shih, Shelley Halpain. Nature communications. 2022 October;13:6037.

PubMed: 36229429 · PMC: PMC9558009

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