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PathPlus™ LMNA / Lamin A+C Antibody (C-Terminus)

Anti-Lamin A/C antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.

PathPlus™ LMNA / Lamin A+C Antibody (C-Terminus)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Immunofluorescence, Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot
Reactivity:Human, Mouse
Format:Liquid
See all LMNA / Lamin A+C antibodies →
$383.00each
Catalog Number: LS-B2005-50

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Overview

Description
Lamin A+C antibody LS-B2005 is an unconjugated rabbit polyclonal antibody to Lamin A+C (LMNA) (C-Terminus) from mouse. It is reactive with human and mouse. Validated for IF, IHC and WB. Cited in 2 publications.
Application
IF, IHC, IHC-P, WB
Reactivity
Hu, Ms
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
70 kDa lamin | CDCD1 | CMD1A | EMD2 | FPLD | IDC | FPL | FPLD2 | Lamin A/C | Lamin | LFP | LMNA | LMNC | LMN1 | LMNL1 | HGPS | Prelamin-A/C | PRO1 | Lamin A | Lamin A/C-like 1 | LGMD1B | CDDC | CMT2B1 | LDP1
Recommended Dilution: IHC-P
1:50
UniProt Number
P02545
SwissProt
P02545

Target

Target
LMNA / Lamin A+C
Antigen Species
Mouse
Specificity
Recombinant (partial), C-terminal. The immunogen is taken from isoform C and may not cross-react with isoform A.
Epitope
Recombinant (partial), C-terminal. The immunogen is taken from isoform C and may not cross-react with isoform A.
Gene Name
LMNA

Antibody

Host Species
Rabbit
Clonality
Polyclonal
Origin Species
Human

Immunogen

Immunogen
Recombinant mouse LMNA / Lamin A.

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
Phosphate-buffered solution, pH 7.2, 0.09% sodium azide, 50% glycerol.
Volume
50 Microliter
Animal Free
No
Carrier-Free
Yes
Preservative
Yes
Purification Method
Affinity Purified

Storage & Handling

Storage Conditions
Store at 4°C or -20°C. Avoid freeze-thaw cycles.
Recommended Storage Buffer
Phosphate-buffered

Pim-1 kinase-dependent phosphorylation of p21Cip1/WAF1 regulates its stability and cellular localization in H1299 cells. Zhang Y, Wang Z, Magnuson NS. Molecular cancer research : MCR. 2007;5:909-22.

PubMed: 17855660


Chronic mucocutaneous candidiasis caused by a gain-of-function mutation in the STAT1 DNA-binding domain. Takezaki S, Yamada M, Kato M, Park MJ, Maruyama K, Yamazaki Y, Chida N, Ohara O, Kobayashi I, Ariga T. Journal of immunology (Baltimore, Md. : 1950). 2012;189:1521-6.

PubMed: 22730530

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