LSBio
PathPlus™ KRT7 / CK7 / Cytokeratin 7 Antibody (clone rOV-TL12/30)

Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)

PathPlus™ KRT7 / CK7 / Cytokeratin 7 Antibody (clone rOV-TL12/30)

Primary AntibodyLSBio Guarantee
Antibody:Mouse Recombinant Monoclonal
Applications:Flow Cytometry, Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot
Reactivity:Human
Format:Liquid
See all KRT7 / CK7 / Cytokeratin 7 antibodies →
$536.00each
Catalog Number: LS-B16248-100

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Overview

Description
Cytokeratin 7 antibody LS-B16248 is an unconjugated mouse recombinant monoclonal antibody to human Cytokeratin 7 (KRT7 / CK7). Validated for Flow, IHC and WB.
Application
FC, IHC, IHC-P, WB
Reactivity
Hu
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee. ✓
Category
Antibodies > Primary Antibodies > Recombinant Antibodies
Alternative Names
CK-7 | Cytokeratin 7 | CK7 | K2C7 | K7 | Keratin 7 | KRT7 | Keratin-7 | SCL | Type II mesothelial keratin K7 | Cytokeratin-7 | Sarcolectin | Type-II keratin Kb7
Recommended Dilution: FC
1 - 2 µg/10E6 cells
Recommended Dilution: IHC-P
1:100
Recommended Dilution: WB
1 - 2 µg/ml
NCBI GenBank
NP_005547.3

Target

Target
KRT7 / CK7 / Cytokeratin 7
Antigen Species
Human
Specificity
It recognizes an intermediate filament protein (IFP) of 55 kDa , which is identified as cytokeratin 7. This MAb is highly specific to cytokeratin 7 and shows no cross-reaction with other IFPs. Cytokeratin 7 is a basic cytokeratin, which is found in most glandular and transitional epithelia but not in the stratified squamous epithelia. Keratin 7 is expressed in the epithelial cells of ovary, lung, and breast but not of colon, prostate, or gastrointestinal tract. This MAb is highly useful in distinguishing ovarian carcinomas (keratin 7+) from colon carcinomas (keratin 7-).
Epitope
It recognizes an intermediate filament protein (IFP) of 55 kDa , which is identified as cytokeratin 7. This MAb is highly specific to cytokeratin 7 and shows no cross-reaction with other IFPs. Cytokeratin 7 is a basic cytokeratin, which is found in most glandular and transitional epithelia but not in the stratified squamous epithelia. Keratin 7 is expressed in the epithelial cells of ovary, lung, and breast but not of colon, prostate, or gastrointestinal tract. This MAb is highly useful in distinguishing ovarian carcinomas (keratin 7+) from colon carcinomas (keratin 7-).

Antibody

Host Species
Mouse
Clonality
Recombinant Monoclonal
Clone
rOV-TL12/30

Immunogen

Immunogen
Recombinant full-length human KRT7 protein. Antigen Molecular Weight: 55 kDa
Immunogen Type
Full-Length Recombinant Protein

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
10 mM PBS, 0.05% BSA, 0.05% Sodium Azide
Concentration
200 µg/mL
Animal Free
No
Carrier-Free
No
Preservative
Yes
Purification Method
Protein A/G Affinity

Storage & Handling

Storage Conditions
Store at 2°C to 8°C for up to 2 years.
Recommended Storage Buffer
10 mM PBS

Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.