Insulin Antibody
Catalog Number: LS-C121976-100
100 µg / $576.00
Antibody: Mouse Monoclonal
Applications: Immunohistochemistry (general), Immunohistochemistry, Paraffin
Reactivity: Human, Mouse, Rat
Format: Lyophilized
Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE)
PathPlus™ Insulin Antibody (clone IRDN/1980R)
Primary AntibodyLSBio Guarantee
| Antibody: | Rabbit Recombinant Monoclonal |
| Applications: | Immunohistochemistry (general) |
| Reactivity: | Human |
| Format: | Liquid |
$495.00each
Catalog Number: LS-B16284-100
Catalog Number: LS-B16284
For bulk orders or custom formulations:
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- Description
- Insulin antibody LS-B16284 is an unconjugated rabbit recombinant monoclonal antibody to human Insulin. Validated for IHC.
- Application
- IHC
- Reactivity
- Hu
- Intended Use
- Research Use Only
- Guarantees
- This product carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Recombinant Antibodies
- Alternative Names
- INS | IRDN | IDDM2 | Preproinsulin | ILPR | Insulin | MODY10 | Proinsulin
- Recommended Dilution: IHC-P
- 1:100
- UniProt Number
- P01308
- NCBI GenBank
- NM_000207 | NP_000198.1
- SwissProt
- P01308
Target
- Target
- Insulin
- Antigen Species
- Human
- Specificity
- Recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule and the C-terminal basic residue. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids. Deficiency of insulin results in diabetes mellitus. The main storage site for insulin is the pancreatic islets. Antibodies to insulin are important as beta-cell and insulinoma marker.
- Epitope
- Recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule and the C-terminal basic residue. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids. Deficiency of insulin results in diabetes mellitus. The main storage site for insulin is the pancreatic islets. Antibodies to insulin are important as beta-cell and insulinoma marker.
- Gene Name
- INS
Antibody
- Host Species
- Rabbit
- Clonality
- Recombinant Monoclonal
- Clone
- IRDN/1980R
- Origin Species
- Human
Immunogen
- Immunogen
- Recombinant full-length human Insulin protein (IRDN). Antigen Molecular Weight: 6 kDa
- Immunogen Type
- Full-Length Recombinant Protein
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- 10 mM PBS, 0.05% BSA, 0.05% Sodium Azide
- Concentration
- 200 mg/mL
- Animal Free
- No
- Carrier-Free
- No
- Preservative
- Yes
- Purification Method
- Protein A/G Affinity
Storage & Handling
- Storage Conditions
- Store at 2°C to 8°C for up to 2 years.
- Recommended Storage Buffer
- 10 mM PBS
