LSBio
PathPlus™ HNE / Neutrophil Elastase Antibody

Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)

PathPlus™ HNE / Neutrophil Elastase Antibody

Primary AntibodyLSBio Guarantee
Antibody:Sheep Polyclonal
Applications:Immunohistochemistry (general)
Reactivity:Human
Format:Liquid
See all HNE / Neutrophil Elastase antibodies →
$577.00each
Catalog Number: LS-B4244-50

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Overview

Description
Neutrophil Elastase antibody LS-B4244 is an unconjugated sheep polyclonal antibody to human Neutrophil Elastase (HNE). Validated for ELISA, IE and IHC. Cited in 1 publication.
Application
IHC
Reactivity
Hu
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
Bone marrow serine protease | ELA2 | ELANE | Elastase 2, neutrophil | Elastase-2 | HLE | Medullasin | Granulocyte-derived elastase | Neutrophil elastase | NE | Human leukocyte elastase | PMN elastase | PMN-E | SCN1 | Polymorphonuclear elastase | Elastase, neutrophil expressed | GE | Leukocyte elastase | Lysosomal elastase | HNE
Recommended Dilution: IHC-P
5 µg/ml
UniProt Number
P08246
SwissProt
P08246

Target

Target
HNE / Neutrophil Elastase
Antigen Species
Human
Specificity
Recognizes human Elastase, Neutrophil
Epitope
Specific for elastase.
Gene Name
ELANE

Antibody

Host Species
Sheep
Clonality
Polyclonal
Origin Species
Human

Immunogen

Immunogen
Neutrophil elastase (active-site blocked) prepared from human sputum.

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
10 mM HEPES, pH 7.4, 0.15 M NaCl, 50% Glycerol
Animal Free
No
Carrier-Free
Yes
Purification Method
Ion Exchange Chromatography

Storage & Handling

Storage Conditions
Short term: store at 4°C. Long term: aliquot and store at -20°C. Avoid freeze-thaw cycles.
Recommended Storage Buffer
10 mM HEPES, 0.15 M NaCl
Intrarenal Toll-like receptor 4 and Toll-like receptor 2 expression correlates with injury in antineutrophil cytoplasmic antibody-associated vasculitis. O'Sullivan KM, Ford SL, Longano A, Kitching AR, Holdsworth SR. American journal of physiology. Renal physiology. 2018 November;315:F1283-F1294. PubMed: 29923769 PMC: PMC6293285

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