LSBio
PathPlus™ HAVCR1 / KIM-1 Antibody (aa200-300)

Anti-TIM-1 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

PathPlus™ HAVCR1 / KIM-1 Antibody (aa200-300)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot
Reactivity:Human, Mouse
Format:Liquid
See all HAVCR1 / KIM-1 antibodies →
$383.00each
Catalog Number: LS-B2031-50

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Overview

Description
KIM-1 antibody LS-B2031 is an unconjugated rabbit polyclonal antibody to KIM-1 (HAVCR1) (aa200-300) from human. It is reactive with human and mouse. Validated for IHC and WB. Cited in 1 publication.
Application
IHC, IHC-P, WB
Reactivity
Hu, Ms
Predicted Reactivity
Non-Human Primate
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
HAVCR-1 | HAVCR1 | KIM-1 | Kidney injury molecule 1 | KIM1 | T-cell membrane protein 1 | TIM1 | TIMD1 | TIM-1 | HAVCR | TIMD-1 | CD365
Recommended Dilution: IHC-P
2.5 - 5 µg/ml
Recommended Dilution: WB
1 - 3 µg/ml
UniProt Number
Q96D42
SwissProt
Q96D42

Target

Target
HAVCR1 / KIM-1
Antigen Species
Human
Specificity
A portion of amino acids 200-300 of human HAVCR1 protein was used as the immunogen.
Epitope
The peptide used to produce this antibody is 100% homologous in human, 93% in vervet/green monkey and 80% in chimp. Furthermore, the peptide sequence is conserved across HAVCR1 isoform a (364 amino acids, accession NP_036338) and HAVCR1 isoform CRA_a (194 amino acids, accession EAW61615.1). As isoforms of different molecular weights have been described for this protein, the molecular weight observed in western blots may vary depending on the forms present.
Gene Name
HAVCR1

Antibody

Host Species
Rabbit
Clonality
Polyclonal
Origin Species
Human

Immunogen

Immunogen
A synthetic peptide of human HAVCR1/KIM-1 protein was used as the immunogen. This sequence detects both isoform a and isoform CRA_a (accessions NP_036338 and EAW61615.1 respectively). Percent identity by BLAST analysis: Human, Gorilla (100%); Monkey (93%); Dog (80%).
Immunogen Type
Synthetic Peptide (Linear)

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, 0.05% Sodium Azide
Concentration
1 mg/mL
Animal Free
No
Carrier-Free
Yes
Preservative
Yes
Purification Method
Protein G Affinity

Storage & Handling

Storage Conditions
Short term: store at 4°C. Long term: aliquot and store at -20°C. Avoid freeze-thaw cycles.
Recommended Storage Buffer
PBS
Urinary KIM-1 Correlates with the Subclinical Sequelae of Tubular Damage Persisting after the Apparent Functional Recovery from Intrinsic Acute Kidney Injury. Cristina Cuesta, Isabel Fuentes-Calvo, Sandra M Sancho-Martinez, Floris A Valentijn, Annette Düwel, Omar A Hidalgo-Thomas, Consuelo Agüeros-Blanco, Adalberto Benito-Hernández, María A Ramos-Barron, Carlos Gómez-Alamillo, Manuel Arias, Tri Q Nguyen, Roel Goldschmeding, Carlos Martínez-Salgado, Francisco J López-Hernández. Biomedicines. 2022 May;10. PubMed: 35625842 PMC: PMC9139078

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