LSBio
PathPlus™ GLP2R Antibody (N-Terminus)

Brain, hippocampus CA2

PathPlus™ GLP2R Antibody (N-Terminus)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Immunohistochemistry (general)
Reactivity:Guinea Pig, Human, Non-Human Primate
Format:Liquid
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$449.00each
Catalog Number: LS-A1312-50

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Overview

Description
GLP2R antibody LS-A1312 is an unconjugated rabbit polyclonal antibody to GLP2R (N-Terminus) from human. It is reactive with human, guinea pig and monkey. Validated for ICC, IF, IHC, IP and WB. Cited in 6 publications.
Application
IHC
Reactivity
GP, Hu, NHP
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
GLP-2-R | GLP-2 receptor | GLP-2R | Glp2 receptor | GLP2R
Recommended Dilution: IHC-P
10 - 20 µg/ml
UniProt Number
O95838
SwissProt
O95838

Target

Target
GLP2R
Antigen Species
Human
Specificity
Human GLP2R. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Epitope
Human GLP2R. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Gene Name
GLP2R

Antibody

Host Species
Rabbit
Clonality
Polyclonal

Immunogen

Immunogen
Synthetic 18 amino acid peptide from N-Terminus extracellular domain of human GLP2R. Percent identity with other species by BLAST analysis: Human, Gorilla, Monkey, Marmoset (100%); Gibbon (94%); Bovine, Dog, Elephant, Panda, Pig (89%); Bat, Rabbit (83%).
Immunogen Type
Synthetic Peptide (Linear)

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, 0.1% Sodium Azide
Concentration
1 mg/mL
Animal Free
No
Carrier-Free
Yes
Preservative
Yes
Purification Method
Affinity Purified

Storage & Handling

Storage Conditions
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Recommended Storage Buffer
PBS

GLP-2 receptor localizes to enteric neurons and endocrine cells expressing vasoactive peptides and mediates increased blood flow. Guan X, Karpen HE, Stephens J, Bukowski JT, Niu S, Zhang G, Stoll B, Finegold MJ, Holst JJ, Hadsell D, Hadsell DL, Nichols BL, Burrin DG. Gastroenterology. 2006;130:150-64.

PubMed: 16401478


Glucagon-like peptide-2 modulates neurally evoked mucosal chloride secretion in guinea pig small intestine in vitro. Baldassano S, Liu S, Qu MH, Mul F, Wood JD. American journal of physiology. Gastrointestinal and liver physiology. 2009;297:G800-5.

PubMed: 19628655 · PMC: PMC2763802


Acute effects of the glucagon-like peptide 2 analogue, teduglutide, on intestinal adaptation in short bowel syndrome. Thymann T, Stoll B, Mecklenburg L, Burrin DG, Vegge A, Qvist N, Eriksen T, Jeppesen PB, Sangild PT. Journal of pediatric gastroenterology and nutrition. 2014 Jun;58:694-702.

PubMed: 24399211


Glugacon-like peptide-2: broad receptor expression, limited therapeutic effect on intestinal inflammation and novel role in liver regeneration. El-Jamal N, Erdual E, Neunlist M, Koriche D, Dubuquoy C, Maggiotto F, Chevalier J, Berrebi D, Dubuquoy L, Boulanger E, Cortot A, Desreumaux P. American journal of physiology. Gastrointestinal and liver physiology. Aug;307:G274-85.

PubMed: 24875097


Influence of Cane Molasses Inclusion to Dairy Cow Diets during the Transition Period on Rumen Epithelial Development. William F Miller, Evan C Titgemeyer, Tiruvoor G Nagaraja, Daniel H M Watanabe, Luana D Felizari, Danilo D Millen, Zachary K Smith, Bradley J Johnson. Animals: an open access journal from MDPI. 2021 April;11.

PubMed: 33923260 · PMC: PMC8145355


GLP-2 Is Locally Produced From Human Islets and Balances Inflammation Through an Inter-Islet-Immune Cell Crosstalk. Wei He, Osmond D Rebello, Antonia Henne, Fabian Nikolka, Thomas Klein, Kathrin Maedler. Frontiers in endocrinology. 2021 July;12:697120.

PubMed: 34290670 · PMC: PMC8287580

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